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Catalog Number:
15276
CAS Number:
269396-59-0
Boc-3,4-difluoro-D-β-homophenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-D-β-HomoPhe(3,4-DiF)-OH, Boc-(R-3-amino-4-(3,4-difluorophenyl)butyric acid
Documents
$154.93 /100MG
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Product Information

Boc-3,4-difluoro-D-b-homophenylalanine is a specialized amino acid derivative that plays a significant role in peptide synthesis and drug development. This compound is particularly valued in the pharmaceutical industry for its unique fluorinated structure, which enhances the bioactivity and stability of peptides. Researchers utilize Boc-3,4-difluoro-D-b-homophenylalanine to create novel therapeutic agents, especially in the development of targeted treatments for various diseases, including cancer and metabolic disorders. Its ability to mimic natural amino acids while providing distinct advantages in binding affinity makes it a preferred choice for medicinal chemists.

Additionally, this compound's protective Boc (tert-butyloxycarbonyl) group allows for selective deprotection during synthesis, facilitating the creation of complex peptide sequences. Its application extends to the fields of biochemistry and molecular biology, where it aids in the study of protein interactions and functions. With its unique properties and versatility, Boc-3,4-difluoro-D-b-homophenylalanine stands out as a valuable tool for researchers aiming to innovate in peptide-based therapies.

Synonyms
Boc-D-β-HomoPhe(3,4-DiF)-OH, Boc-(R-3-amino-4-(3,4-difluorophenyl)butyric acid
CAS Number
269396-59-0
Purity
≥ 99% (HPLC)
Molecular Formula
C15H19F2NO4
Molecular Weight
315.32
MDL Number
MFCD01860952
PubChem ID
21911215
Melting Point
132 - 136 ?C
Appearance
White powder
Optical Rotation
[a]21D = 13 ± 1 ° (C=1 in EtOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-D-β-HomoPhe(3,4-DiF)-OH, Boc-(R-3-amino-4-(3,4-difluorophenyl)butyric acid
CAS Number
269396-59-0
Purity
≥ 99% (HPLC)
Molecular Formula
C15H19F2NO4
Molecular Weight
315.32
MDL Number
MFCD01860952
PubChem ID
21911215
Melting Point
132 - 136 ?C
Appearance
White powder
Optical Rotation
[a]21D = 13 ± 1 ° (C=1 in EtOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-3,4-difluoro-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of novel therapeutic agents. Its unique fluorinated structure can enhance the stability and bioactivity of peptides.
  • Drug Development: In pharmaceutical research, it is used to create compounds with improved pharmacological properties. The incorporation of fluorine can lead to increased metabolic stability and better binding affinity to target proteins.
  • Biochemical Studies: Researchers employ this chemical to study protein interactions and enzyme mechanisms. Its distinct characteristics allow for more precise investigations into biological processes.
  • Material Science: The compound finds applications in the development of advanced materials, such as polymers and coatings, where its fluorinated properties can impart desirable characteristics like chemical resistance and durability.
  • Diagnostics: In the field of diagnostics, it can be utilized in the design of imaging agents or contrast media, enhancing the visibility of biological structures in medical imaging techniques.

Citations