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Catalog Number:
15274
CAS Number:
269396-57-8
Fmoc-3,4-dichloro-D-ॆ-homophenylalanine
Purity:
≥ 99% (HPLC, Chiral purity)
Synonym(s):
Fmoc-D-β-HomoPhe(3,4-DiCl)-OH, Fmoc-(R-3-amino-4-(3,4-dichlorophenyl)butyric acid
Documents
$72.31 /25MG
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Product Information

Fmoc-3,4-dichloro-D-b-homophenylalanine is a specialized amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective modification of amino acids during solid-phase peptide synthesis. Its structure, characterized by the presence of dichlorophenyl groups, enhances its reactivity and stability, making it an excellent choice for researchers aiming to create complex peptides with specific functionalities.

This compound is particularly valuable in the pharmaceutical industry, where it serves as a building block for the synthesis of bioactive peptides and potential therapeutics. Its unique properties allow for the development of peptides with improved efficacy and selectivity, which are crucial in drug design. Additionally, Fmoc-3,4-dichloro-D-b-homophenylalanine can be employed in various research applications, including studies on protein interactions and structure-function relationships. With its robust performance in peptide synthesis, this compound stands out as an essential tool for researchers and industry professionals alike.

Synonyms
Fmoc-D-β-HomoPhe(3,4-DiCl)-OH, Fmoc-(R-3-amino-4-(3,4-dichlorophenyl)butyric acid
CAS Number
269396-57-8
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C25H21Cl2NO4
Molecular Weight
470.35
MDL Number
MFCD01860950
PubChem ID
53397932
Melting Point
144-150 °C
Appearance
White powder
Optical Rotation
[a]D20 = +20 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-β-HomoPhe(3,4-DiCl)-OH, Fmoc-(R-3-amino-4-(3,4-dichlorophenyl)butyric acid
CAS Number
269396-57-8
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C25H21Cl2NO4
Molecular Weight
470.35
MDL Number
MFCD01860950
PubChem ID
53397932
Melting Point
144-150 °C
Appearance
White powder
Optical Rotation
[a]D20 = +20 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3,4-dichloro-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide chains efficiently.
  • Drug Development: Its unique structure makes it valuable in the design of novel pharmaceuticals, especially in developing compounds that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The compound can be used to create bioconjugates, which are essential in developing targeted drug delivery systems and diagnostic tools, improving the precision of treatments.
  • Research in Neuroscience: It plays a role in studying neuropeptides, contributing to understanding neurological disorders and potentially leading to new treatment strategies.
  • Protein Engineering: This chemical is instrumental in modifying proteins to study their functions and interactions, aiding in the development of biotechnological applications and therapeutic proteins.

Citations