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Catalog Number:
15121
CAS Number:
478183-58-3
Fmoc-3-chloro-L-tyrosine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-m-chloro-L-Tyr-OH
Documents
$50.00 /250MG
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Product Information

Fmoc-3-chloro-L-tyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. Its unique structure, characterized by the presence of a chloro substituent on the aromatic ring, enhances its reactivity and allows for the incorporation of halogenated residues into peptides, making it invaluable in the design of bioactive compounds. Researchers in medicinal chemistry and biochemistry can leverage Fmoc-3-chloro-L-tyrosine to create peptides with improved pharmacological properties, including increased stability and specificity.

In addition to its applications in peptide synthesis, Fmoc-3-chloro-L-tyrosine serves as a building block for the development of novel therapeutic agents and can be used in the study of protein interactions and enzyme activity. Its ability to facilitate the introduction of chlorine into peptide sequences opens new avenues for the exploration of structure-activity relationships in drug design. With its robust profile and practical applications, Fmoc-3-chloro-L-tyrosine is an essential tool for researchers aiming to innovate in the fields of pharmaceuticals and biotechnology.

Synonyms
Fmoc-m-chloro-L-Tyr-OH
CAS Number
478183-58-3
Purity
≥ 98% (HPLC)
Molecular Formula
C24H20ClNO5
Molecular Weight
437.88
MDL Number
MFCD02682261
PubChem ID
53421061
Melting Point
162 - 176 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -22 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-m-chloro-L-Tyr-OH
CAS Number
478183-58-3
Purity
≥ 98% (HPLC)
Molecular Formula
C24H20ClNO5
Molecular Weight
437.88
MDL Number
MFCD02682261
PubChem ID
53421061
Melting Point
162 - 176 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -22 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-chloro-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), enhancing the efficiency and yield of target peptides.
  • Drug Development: Its unique structure allows for the incorporation of chlorine into peptides, which can improve the pharmacological properties of potential drug candidates, making them more effective in targeting specific biological pathways.
  • Bioconjugation: Fmoc-3-chloro-L-tyrosine can be used in bioconjugation processes, facilitating the attachment of peptides to various biomolecules, which is crucial in developing targeted therapies and diagnostics.
  • Research in Neuroscience: Due to its structural similarity to natural neurotransmitters, it is employed in studies aimed at understanding receptor interactions and signaling pathways in the nervous system.
  • Protein Engineering: This compound is instrumental in modifying proteins to study their functions or to create novel proteins with enhanced properties, providing insights into protein behavior and interactions.

Citations