Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
15120
CAS Number:
220497-48-3
Fmoc-3-bromo-L-phenylalanine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-L-Phe(3-Br)-OH, Fmoc-3-bromo-L-Phe-OH, (S-2-Fmoc-2-amino-3-(3-bromophenyl)propionic acid
Documents
$86.23 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-3-bromo-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which enhances its stability and solubility, making it an excellent choice for solid-phase peptide synthesis. Its bromine substitution at the phenyl group allows for further functionalization, enabling researchers to explore a variety of chemical modifications that can lead to novel therapeutic agents.

In the pharmaceutical industry, Fmoc-3-bromo-L-phenylalanine is particularly valuable for the synthesis of bioactive peptides, which are crucial in developing new drugs for various diseases. Its ability to facilitate the introduction of specific functionalities into peptide chains opens up possibilities for creating targeted therapies and improving drug efficacy. Researchers appreciate its ease of use and the efficiency it brings to peptide synthesis, making it a preferred choice for both academic and industrial applications.

Synonyms
Fmoc-L-Phe(3-Br)-OH, Fmoc-3-bromo-L-Phe-OH, (S-2-Fmoc-2-amino-3-(3-bromophenyl)propionic acid
CAS Number
220497-48-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C24H20BrNO4
Molecular Weight
466.3
MDL Number
MFCD01311744
PubChem ID
44181942
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(3-Br)-OH, Fmoc-3-bromo-L-Phe-OH, (S-2-Fmoc-2-amino-3-(3-bromophenyl)propionic acid
CAS Number
220497-48-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C24H20BrNO4
Molecular Weight
466.3
MDL Number
MFCD01311744
PubChem ID
44181942
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-bromo-L-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide sequences efficiently.
  • Drug Development: It plays a significant role in medicinal chemistry, where its unique bromine substituent can enhance the biological activity of peptide-based drugs, making it valuable in the pharmaceutical industry.
  • Bioconjugation: The compound is used in bioconjugation techniques, where it can be attached to biomolecules, facilitating the development of targeted drug delivery systems or diagnostic agents.
  • Research in Protein Engineering: It is employed in studies aimed at modifying protein structures, helping scientists understand protein function and stability, which is crucial in biotechnology and enzyme engineering.
  • Fluorescent Labeling: Fmoc-3-bromo-L-phenylalanine can be used in fluorescent labeling applications, aiding in the visualization of peptides in biological assays, which is essential for various research applications.

Citations