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Catalog Number:
15116
CAS Number:
478183-71-0
Fmoc-3-nitro-D-phenylalanine
Purity:
≥ 98% (HPLC, Chiral purity)
Synonym(s):
Fmoc-D-Phe(3-NO2)-OH, Fmoc-m-nitro-D-Phe-OH, (R-2-Fmoc-2-amino-3-(3-nitrophenyl)propionic acid
Documents
$86.23 /1G
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Product Information

Fmoc-3-nitro-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amine functionalities during the synthesis of complex peptides. Its unique nitro group enhances the compound's reactivity, making it an excellent choice for researchers looking to incorporate specific functionalities into their peptide sequences.

In the pharmaceutical industry, Fmoc-3-nitro-D-phenylalanine is particularly valuable for the development of peptide-based therapeutics, where precise amino acid incorporation is essential. Its ability to facilitate the synthesis of bioactive peptides allows for the exploration of novel drug candidates with improved efficacy and specificity. Additionally, this compound can be employed in various research applications, including studies on protein interactions and enzyme activity, making it a vital tool for both academic and industrial laboratories.

Synonyms
Fmoc-D-Phe(3-NO2)-OH, Fmoc-m-nitro-D-Phe-OH, (R-2-Fmoc-2-amino-3-(3-nitrophenyl)propionic acid
CAS Number
478183-71-0
Purity
≥ 98% (HPLC, Chiral purity)
Molecular Formula
C24H20N2O6
Molecular Weight
432.0
MDL Number
MFCD01317715
PubChem ID
6915693
Appearance
White to off-white solid
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Phe(3-NO2)-OH, Fmoc-m-nitro-D-Phe-OH, (R-2-Fmoc-2-amino-3-(3-nitrophenyl)propionic acid
CAS Number
478183-71-0
Purity
≥ 98% (HPLC, Chiral purity)
Molecular Formula
C24H20N2O6
Molecular Weight
432.0
MDL Number
MFCD01317715
PubChem ID
6915693
Appearance
White to off-white solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-nitro-D-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique structure makes it valuable in the design of novel therapeutic agents, particularly in targeting specific biological pathways, enhancing drug efficacy and selectivity.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking peptides to other biomolecules, which is essential in developing targeted drug delivery systems and diagnostic tools.
  • Research in Neuroscience: It is utilized in studies related to neurobiology, particularly in understanding the role of peptides in neurological functions and disorders, contributing to advancements in neuropharmacology.
  • Fluorescent Labeling: The compound can be modified for use in fluorescent labeling techniques, aiding in the visualization of proteins and peptides in cellular studies, which is crucial for understanding cellular mechanisms.

Citations