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Catalog Number:
15106
CAS Number:
273221-75-3
Boc-3-iodo-L-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Phe(3-I)-OH, Boc-3-iodo-L-Phe-OH, (S-Boc-2-amino-3-(3-iodophenyl)propionic acid
Documents
$194.99 /1G
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Product Information

Boc-3-iodo-L-phenylalanine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and medicinal chemistry. This compound is particularly valued for its ability to introduce iodine into peptide sequences, which can enhance the biological activity and stability of therapeutic peptides. Its unique structure, featuring a Boc (tert-butyloxycarbonyl) protecting group, allows for selective reactions, making it an essential building block in the development of novel pharmaceuticals. Researchers utilize Boc-3-iodo-L-phenylalanine in the synthesis of peptide-based drugs, where the incorporation of iodine can facilitate imaging techniques or improve the pharmacokinetic properties of the resulting compounds.

In addition to its applications in drug development, Boc-3-iodo-L-phenylalanine is also employed in various research settings, including studies focused on protein interactions and enzyme activity. Its ability to serve as a precursor for further modifications makes it a valuable tool for chemists looking to explore new therapeutic avenues. With its combination of stability, reactivity, and functional versatility, Boc-3-iodo-L-phenylalanine stands out as a key compound for professionals in the pharmaceutical and biochemical fields.

Synonyms
Boc-L-Phe(3-I)-OH, Boc-3-iodo-L-Phe-OH, (S-Boc-2-amino-3-(3-iodophenyl)propionic acid
CAS Number
273221-75-3
Purity
≥ 98% (HPLC)
Molecular Formula
C14H18INO4
Molecular Weight
391.2
MDL Number
MFCD01860644
PubChem ID
21851057
Melting Point
111-120 ?C
Appearance
White powder
Optical Rotation
[a]D25 = +18 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Phe(3-I)-OH, Boc-3-iodo-L-Phe-OH, (S-Boc-2-amino-3-(3-iodophenyl)propionic acid
CAS Number
273221-75-3
Purity
≥ 98% (HPLC)
Molecular Formula
C14H18INO4
Molecular Weight
391.2
MDL Number
MFCD01860644
PubChem ID
21851057
Melting Point
111-120 ?C
Appearance
White powder
Optical Rotation
[a]D25 = +18 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-3-iodo-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of peptide-based drugs, enhancing the efficiency of drug discovery.
  • Bioconjugation: It is used in bioconjugation processes, allowing researchers to attach biomolecules to drugs or imaging agents, which is crucial in targeted therapy and diagnostics.
  • Protein Engineering: The compound plays a significant role in modifying proteins, helping scientists create novel proteins with enhanced properties for therapeutic applications.
  • Research in Neuroscience: Its unique structure allows for the study of neurotransmitter interactions, providing insights into neurological disorders and potential treatments.
  • Radiolabeling: Boc-3-iodo-L-phenylalanine is used in radiolabeling techniques, facilitating the development of imaging agents for PET scans, which are essential in cancer diagnostics.

Citations