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Catalog Number:
15053
CAS Number:
653589-37-8
Fmoc-(2S,4R-4-hydroxypiperidine-2-carboxylic acid
Purity:
≥ 97% (HPLC)
Documents
$113.87 /100MG
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Product Information

Fmoc-(2S,4R)-4-hydroxypiperidine-2-carboxylic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protective group, which is crucial for the selective protection of amines during the synthesis of peptides. Its unique stereochemistry enhances its utility in the development of bioactive compounds, allowing researchers to create complex molecular architectures with improved efficacy and selectivity.

In practical applications, Fmoc-(2S,4R)-4-hydroxypiperidine-2-carboxylic acid is employed in the synthesis of various pharmaceuticals and biologically active molecules. Its ability to facilitate the formation of peptide bonds while maintaining stability under standard reaction conditions makes it an essential reagent for chemists working in drug discovery and development. Additionally, its favorable properties compared to similar compounds, such as enhanced solubility and reactivity, position it as a preferred choice for researchers aiming to streamline their synthetic processes.

CAS Number
653589-37-8
Purity
≥ 97% (HPLC)
Molecular Formula
C21H21NO5
Molecular Weight
367.4
MDL Number
MFCD04112684
PubChem ID
4712575
Appearance
White powder
Optical Rotation
[α]D20 = -9 +/- 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
CAS Number
653589-37-8
Purity
≥ 97% (HPLC)
Molecular Formula
C21H21NO5
Molecular Weight
367.4
MDL Number
MFCD04112684
PubChem ID
4712575
Appearance
White powder
Optical Rotation
[α]D20 = -9 +/- 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(2S,4R)-4-hydroxypiperidine-2-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing chemists to selectively modify amino acids without affecting others.
  • Drug Development: It plays a crucial role in the development of pharmaceutical compounds, particularly in creating peptide-based drugs that can target specific biological pathways.
  • Bioconjugation: The chemical is used to attach biomolecules, such as antibodies or enzymes, to therapeutic agents, enhancing their efficacy and targeting capabilities in treatments.
  • Research in Neuroscience: Its derivatives are explored for potential applications in studying neurotransmitter systems, providing insights into neurological disorders.
  • Material Science: The compound is also investigated for its potential in creating novel materials with specific properties, such as improved biocompatibility for medical devices.

Citations