Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
15038
CAS Number:
957311-37-4
Fmoc-L-glutamic acid α-7-amido-4-methylcoumarin
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-glutamic acid α-7-amido-4-methylcoumarin
Documents
$106.96 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-L-glutamic acid a-7-amido-4-methylcoumarin is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This derivative of glutamic acid features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which facilitates the selective coupling of amino acids in solid-phase peptide synthesis. Its unique structure, incorporating a 4-methylcoumarin moiety, enhances its utility in fluorescence-based assays, making it an excellent choice for researchers focusing on bioimaging and drug delivery systems.

The compound's ability to serve as a fluorescent probe allows for real-time monitoring of peptide interactions and cellular processes, providing valuable insights in biochemical research. Additionally, its stability and compatibility with various reaction conditions make it a preferred choice for synthetic chemists looking to develop novel peptides with specific functionalities. With its dual role as a building block and a fluorescent marker, Fmoc-L-glutamic acid a-7-amido-4-methylcoumarin stands out in the field of chemical biology and medicinal chemistry.

Synonyms
Fmoc-L-glutamic acid α-7-amido-4-methylcoumarin
CAS Number
957311-37-4
Purity
≥ 98% (HPLC)
Molecular Formula
C30H26N2O7
Molecular Weight
526.54
MDL Number
MFCD03791062
PubChem ID
3400727
Melting Point
214-223 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -50 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-glutamic acid α-7-amido-4-methylcoumarin
CAS Number
957311-37-4
Purity
≥ 98% (HPLC)
Molecular Formula
C30H26N2O7
Molecular Weight
526.54
MDL Number
MFCD03791062
PubChem ID
3400727
Melting Point
214-223 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -50 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-glutamic acid a-7-amido-4-methylcoumarin is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences with high purity.
  • Fluorescent Probes: Its unique structure enables its use as a fluorescent probe in biochemical assays, helping researchers visualize and track biological processes in real-time.
  • Drug Development: The compound is explored in medicinal chemistry for the development of new drugs, particularly those targeting specific proteins, due to its ability to modify biological activity.
  • Bioconjugation: It is applied in bioconjugation techniques, linking biomolecules to enhance their stability and efficacy, which is crucial in therapeutic applications.
  • Research in Neuroscience: The compound is utilized in studies related to neurotransmitter signaling, aiding in the understanding of neurological pathways and potential treatments for neurodegenerative diseases.

Citations