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Catalog Number:
15037
CAS Number:
185547-51-7
Fmoc-L-Glu-pNA
Purity:
≥ 99% (HPLC)
Documents
$72.31 /250MG
Pack Size Availability Price
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Product Information

Fmoc-L-Glu-pNA is a versatile compound widely utilized in peptide synthesis and biochemical research. This derivative of glutamic acid features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during the synthesis of peptides. The presence of the p-nitroaniline moiety enhances its utility in various applications, particularly in the development of peptide-based assays and drug discovery. Researchers appreciate its ability to facilitate the study of enzyme kinetics and protein interactions, making it a valuable tool in both academic and industrial laboratories.

In addition to its role in peptide synthesis, Fmoc-L-Glu-pNA is also employed in the development of fluorescent probes and biosensors, where its unique structural characteristics allow for enhanced detection capabilities. Its stability and ease of use make it a preferred choice for professionals looking to streamline their research processes. With its broad range of applications, Fmoc-L-Glu-pNA stands out as a critical compound for advancing research in biochemistry and molecular biology.

CAS Number
185547-51-7
Purity
≥ 99% (HPLC)
Molecular Formula
C26H23N3O7
Molecular Weight
489.48
MDL Number
MFCD04112655
PubChem ID
4712544
Melting Point
219-225 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -33 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
CAS Number
185547-51-7
Purity
≥ 99% (HPLC)
Molecular Formula
C26H23N3O7
Molecular Weight
489.48
MDL Number
MFCD04112655
PubChem ID
4712544
Melting Point
219-225 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -33 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-Glu-pNA is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences for studying protein functions and interactions.
  • Enzyme Activity Assays: It is commonly used in assays to measure the activity of enzymes, particularly those involved in proteolysis, providing valuable insights into metabolic processes.
  • Drug Development: In pharmaceutical research, it aids in the design of peptide-based drugs, enhancing the efficacy and specificity of therapeutic agents.
  • Bioconjugation: The compound facilitates the conjugation of peptides to other molecules, such as drugs or imaging agents, improving targeted delivery in biomedical applications.
  • Fluorescent Labeling: Fmoc-L-Glu-pNA can be used in fluorescent labeling techniques, enabling visualization of proteins in various biological studies, which is crucial for understanding cellular mechanisms.

Citations