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Catalog Number:
14832
CAS Number:
180675-08-5
Fmoc-L-aspartic acid β-methylpentyl ester
Purity:
≥ 99% (Assay)
Synonym(s):
Fmoc-L-Asp(OMpe)-OH, (S)-3-(Fmoc-amino)-4-(4-methylpentyloxy)-4-oxobutyric acid
Documents
$80.50 /250MG
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Product Information

Fmoc-L-aspartic acid b-methylpentyl ester is a versatile compound widely utilized in peptide synthesis and drug development. This derivative of aspartic acid features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for enhanced solubility and stability, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry. The b-methylpentyl ester moiety contributes to its lipophilicity, facilitating the incorporation of this compound into various biological systems.

In practical applications, Fmoc-L-aspartic acid b-methylpentyl ester is particularly valuable in the synthesis of bioactive peptides and pharmaceuticals. Its ability to undergo smooth deprotection under mild conditions allows for the efficient assembly of complex peptide sequences. Researchers have successfully employed this compound in the development of peptide-based therapeutics, including those targeting neurological disorders and cancer. With its favorable properties and broad applicability, this compound stands out as a crucial building block for innovative drug design and development.

Synonyms
Fmoc-L-Asp(OMpe)-OH, (S)-3-(Fmoc-amino)-4-(4-methylpentyloxy)-4-oxobutyric acid
CAS Number
180675-08-5
Purity
≥ 99% (Assay)
Molecular Formula
C25H29NO6
Molecular Weight
439.51
MDL Number
MFCD10001333
PubChem ID
76401347
Melting Point
97 - 111 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -22 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Asp(OMpe)-OH, (S)-3-(Fmoc-amino)-4-(4-methylpentyloxy)-4-oxobutyric acid
CAS Number
180675-08-5
Purity
≥ 99% (Assay)
Molecular Formula
C25H29NO6
Molecular Weight
439.51
MDL Number
MFCD10001333
PubChem ID
76401347
Melting Point
97 - 111 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -22 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-aspartic acid b-methylpentyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptide structures.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially those targeting neurological disorders, by facilitating the incorporation of aspartic acid into therapeutic peptides.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the efficacy of drug delivery systems.
  • Research in Protein Engineering: It plays a role in protein engineering, allowing researchers to modify proteins for better stability and activity, which is crucial in developing biotechnological applications.
  • Analytical Chemistry: This ester is utilized in analytical methods to study protein interactions and stability, providing insights that are essential for various biochemical applications.

Citations