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Catalog Number:
14831
CAS Number:
145038-53-5
Fmoc-L-aspartic acid β-methyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Asp(OMe)-OH
Documents
$29.34 /1G
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Product Information

Fmoc-L-aspartic acid b-methyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which is crucial for the selective protection of the amino group during the synthesis of peptides. Its unique structure not only enhances stability but also facilitates the formation of complex peptide chains, making it an essential building block in the production of pharmaceuticals and biologically active compounds.

Researchers and industry professionals appreciate Fmoc-L-aspartic acid b-methyl ester for its ability to improve the efficiency of peptide coupling reactions, leading to higher yields and purities in synthesized products. Its applications extend to the development of therapeutic peptides, where precise amino acid sequences are critical for biological activity. Additionally, this compound is recognized for its compatibility with various coupling reagents, ensuring versatility in diverse synthetic pathways. With its proven track record in enhancing peptide synthesis, Fmoc-L-aspartic acid b-methyl ester stands out as a valuable asset in both academic and industrial laboratories.

Synonyms
Fmoc-L-Asp(OMe)-OH
CAS Number
145038-53-5
Purity
≥ 98% (HPLC)
Molecular Formula
C20H19NO6
Molecular Weight
369.37
MDL Number
MFCD08458573
PubChem ID
22970398
Melting Point
> 120 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -33.0 ± 3º (C=1% in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Asp(OMe)-OH
CAS Number
145038-53-5
Purity
≥ 98% (HPLC)
Molecular Formula
C20H19NO6
Molecular Weight
369.37
MDL Number
MFCD08458573
PubChem ID
22970398
Melting Point
> 120 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -33.0 ± 3º (C=1% in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-aspartic acid b-methyl ester is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing efficiency and yield.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing peptide-based drugs, offering improved stability and bioavailability compared to other amino acid derivatives.
  • Biotechnology: Researchers use this compound in the modification of proteins, which is essential for creating novel biomaterials and therapeutic agents.
  • Diagnostic Tools: It is employed in the development of diagnostic assays, particularly in the detection of specific biomolecules, contributing to advancements in medical diagnostics.
  • Research Applications: The compound is valuable in academic and industrial research for studying enzyme activity and protein interactions, providing insights into biological processes.

Citations