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Catalog Number:
14413
CAS Number:
103542-47-8
Boc-L-Valine chloromethyl ketone
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Val-CMK
Documents
$160.34 /100MG
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Product Information

Boc-L-Valine chloromethyl ketone is a versatile compound widely utilized in the synthesis of peptide-based pharmaceuticals and research applications. This compound serves as a valuable building block in the development of various bioactive molecules, particularly in the field of medicinal chemistry. Its unique structure, featuring a tert-butyl carbamate protecting group, allows for selective reactions, making it an ideal choice for chemists looking to create complex peptide sequences with high specificity and yield.

In addition to its role in peptide synthesis, Boc-L-Valine chloromethyl ketone is also employed in the production of prodrugs and other derivatives that enhance drug solubility and bioavailability. Researchers appreciate its stability under standard laboratory conditions, which facilitates its use in various organic transformations. The compound's ability to undergo further functionalization opens avenues for the design of novel therapeutic agents, making it a crucial asset for pharmaceutical development and academic research.

Synonyms
Boc-L-Val-CMK
CAS Number
103542-47-8
Purity
≥ 98% (HPLC)
Molecular Formula
C11H20NO3Cl
Molecular Weight
249.73
MDL Number
MFCD11113165
PubChem ID
13919081
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -33 ± 2º (C=1.0, in CHCl3)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Val-CMK
CAS Number
103542-47-8
Purity
≥ 98% (HPLC)
Molecular Formula
C11H20NO3Cl
Molecular Weight
249.73
MDL Number
MFCD11113165
PubChem ID
13919081
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -33 ± 2º (C=1.0, in CHCl3)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-Valine chloromethyl ketone is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences for studies in biochemistry and pharmacology.
  • Drug Development: It is employed in the design of novel pharmaceuticals, particularly in the development of protease inhibitors, which are crucial in treating viral infections.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps to attach biomolecules to surfaces or other molecules, enhancing drug delivery systems and diagnostics.
  • Research on Amino Acid Derivatives: It aids in the exploration of amino acid derivatives, contributing to advancements in nutritional science and metabolic studies.
  • Chiral Synthesis: The compound is significant in chiral synthesis, providing researchers with tools to create enantiomerically pure compounds, which are essential in pharmaceuticals for efficacy and safety.

Citations