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Catalog Number:
14378
CAS Number:
64231-55-6
4-Fluoro-L-phenylalanine methyl ester hydrochloride
Purity:
≥ 99% (HPLC)
Synonym(s):
L-Phe(4-F)-OMe·HCl, p-Fluoro-L-Phe-OMe·HCl, (S-2-Amino-3-(4-fluorophenyl)propionic acid methyl ester hydrochloride
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Product Information

4-Fluoro-L-phenylalanine methyl ester hydrochloride is a versatile compound that plays a significant role in biochemical research and pharmaceutical applications. This amino acid derivative is particularly valued for its ability to serve as a building block in the synthesis of peptides and proteins, enabling researchers to explore the structure-activity relationships of various biomolecules. Its unique fluorine substitution enhances the compound's stability and bioactivity, making it an attractive candidate for drug development and medicinal chemistry.

In addition to its synthetic utility, 4-Fluoro-L-phenylalanine methyl ester hydrochloride is also employed in studies related to neurobiology and metabolic pathways, where it can help elucidate the roles of amino acids in physiological processes. Its properties allow for precise modifications in peptide synthesis, which can lead to the development of novel therapeutics. Researchers and industry professionals can leverage this compound to advance their projects in drug discovery and biochemical analysis, benefiting from its enhanced performance compared to similar compounds.

Synonyms
L-Phe(4-F)-OMe·HCl, p-Fluoro-L-Phe-OMe·HCl, (S-2-Amino-3-(4-fluorophenyl)propionic acid methyl ester hydrochloride
CAS Number
64231-55-6
Purity
≥ 99% (HPLC)
Molecular Formula
C10H12FNO2·HCl
Molecular Weight
233.7
MDL Number
MFCD11113158
PubChem ID
21693993
Melting Point
198 - 200 ?C
Optical Rotation
[a]20D = 16 ± 1 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
L-Phe(4-F)-OMe·HCl, p-Fluoro-L-Phe-OMe·HCl, (S-2-Amino-3-(4-fluorophenyl)propionic acid methyl ester hydrochloride
CAS Number
64231-55-6
Purity
≥ 99% (HPLC)
Molecular Formula
C10H12FNO2·HCl
Molecular Weight
233.7
MDL Number
MFCD11113158
PubChem ID
21693993
Melting Point
198 - 200 ?C
Optical Rotation
[a]20D = 16 ± 1 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Fluoro-L-phenylalanine methyl ester hydrochloride is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a building block in the synthesis of novel pharmaceuticals, particularly in the development of drugs targeting neurological disorders due to its unique fluorine substitution, which can enhance bioactivity.
  • Protein Engineering: It is used in the study of protein structure and function, allowing researchers to introduce fluorinated amino acids into proteins, which can help in understanding protein interactions and stability.
  • Biochemical Research: The compound is valuable in studying metabolic pathways and enzyme kinetics, providing insights into how fluorinated compounds behave in biological systems compared to their non-fluorinated counterparts.
  • Drug Design: It plays a role in structure-activity relationship (SAR) studies, helping medicinal chemists to optimize drug candidates by modifying their chemical properties for better efficacy and reduced side effects.
  • Analytical Chemistry: This chemical is utilized in developing analytical methods for detecting and quantifying amino acids in complex mixtures, benefiting food safety and quality control in the food industry.

Citations