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Catalog Number:
14128
CAS Number:
102089-74-7
Boc-D-phenylglycinol
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
(R-2-(Boc-amino)-2-phenylethanol, Boc-D-Phg-ol
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Product Information

Boc-D-phenylglycinol is a versatile compound widely utilized in the synthesis of pharmaceuticals and fine chemicals. This tert-butyl carbamate derivative is particularly valued for its role as a chiral building block in asymmetric synthesis, enabling researchers to create compounds with specific stereochemical configurations. Its unique structure allows for the introduction of phenyl groups, enhancing the compound's reactivity and selectivity in various chemical reactions.

In the pharmaceutical industry, Boc-D-phenylglycinol is often employed in the development of peptide-based drugs and biologically active molecules, making it essential for researchers focused on drug discovery and development. Its stability under a range of conditions, combined with its ease of handling, makes it an ideal choice for both academic and industrial applications. Additionally, the compound's ability to facilitate the formation of peptide bonds further underscores its significance in medicinal chemistry, providing a reliable pathway for the synthesis of complex molecules.

Synonyms
(R-2-(Boc-amino)-2-phenylethanol, Boc-D-Phg-ol
CAS Number
102089-74-7
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C13H19NO3
Molecular Weight
237.3
MDL Number
MFCD00274205
PubChem ID
5050210
Melting Point
131 - 137 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -39 to -40 º (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(R-2-(Boc-amino)-2-phenylethanol, Boc-D-Phg-ol
CAS Number
102089-74-7
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C13H19NO3
Molecular Weight
237.3
MDL Number
MFCD00274205
PubChem ID
5050210
Melting Point
131 - 137 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -39 to -40 º (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-phenylglycinol is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing chemists to selectively modify amino acids without affecting others. This is crucial for creating complex peptide structures in pharmaceuticals.
  • Drug Development: It plays a significant role in the development of new drugs, particularly those targeting neurological conditions. Its ability to enhance solubility and stability makes it a valuable component in formulation chemistry.
  • Chiral Resolution: Boc-D-phenylglycinol is effective in the chiral resolution of racemic mixtures, which is essential in producing enantiomerically pure compounds for the pharmaceutical industry, ensuring efficacy and safety in drug formulations.
  • Bioconjugation: This chemical is used in bioconjugation techniques, linking biomolecules to drugs or imaging agents. This application is vital in developing targeted therapies and diagnostic tools in medicine.
  • Research in Organic Chemistry: It is frequently employed in organic synthesis as a versatile building block, facilitating the creation of various compounds. This versatility supports advancements in chemical research and innovation.

Citations