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Catalog Number:
12996
CAS Number:
42074-68-0
2-Chlorotrityl chloride resin (1.0-1.2 meq/g, 200-400 mesh)
Synonym(s):
2-Chlorotriphenylmethyl chloride resin
Documents
$25.20 /1G
Pack Size Availability Price
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Product Information

2-Chlorotrityl chloride resin is a highly versatile and efficient reagent widely used in organic synthesis and solid-phase peptide synthesis. With a functional loading of 1.0 - 1.2 mmol/g and a particle size of 200 - 400 mesh, this resin offers excellent accessibility for various chemical reactions. Its unique chlorinated structure allows for selective functionalization, making it an ideal choice for researchers looking to create complex molecules with precision. This resin is particularly beneficial in the pharmaceutical industry for the synthesis of peptide-based drugs, where its high reactivity and stability under various conditions enhance the overall yield and purity of the final product.

In addition to its applications in peptide synthesis, 2-Chlorotrityl chloride resin is also utilized in the preparation of diverse organic compounds, including natural products and heterocycles. Its ability to facilitate the attachment of various functional groups allows chemists to explore a wide range of chemical transformations. The resin's compatibility with automated synthesizers further streamlines the synthesis process, making it a valuable tool for both academic and industrial laboratories. By choosing this resin, professionals can achieve greater efficiency and reliability in their synthetic endeavors.

Synonyms
2-Chlorotriphenylmethyl chloride resin
CAS Number
42074-68-0
MDL Number
MFCD00161760
PubChem ID
94524
Appearance
Yellow beads
Substitution
1.0 - 1.2 meq/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0 - 8 °C
%DVB
1% DVB
General Information
Synonyms
2-Chlorotriphenylmethyl chloride resin
CAS Number
42074-68-0
MDL Number
MFCD00161760
PubChem ID
94524
Appearance
Yellow beads
Substitution
1.0 - 1.2 meq/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0 - 8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chlorotrityl chloride resin is widely utilized in research focused on:

  • Solid-Phase Peptide Synthesis: This resin is essential for synthesizing peptides in a controlled manner, allowing researchers to create complex molecules efficiently.
  • Drug Discovery: It serves as a key component in the development of new pharmaceuticals, aiding in the screening of potential drug candidates through combinatorial chemistry.
  • Bioconjugation: The resin is used to attach biomolecules, such as proteins or nucleic acids, to surfaces or other molecules, enhancing the development of targeted therapies.
  • Polymer Chemistry: It plays a role in creating functionalized polymers, which can be tailored for specific applications in materials science and nanotechnology.
  • Analytical Chemistry: The resin is utilized in the preparation of samples for various analytical techniques, improving the accuracy and efficiency of chemical analysis.

Citations