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Catalog Number:
12930
CAS Number:
102831-44-7
Diethyl (Boc-amino)malonate
Purity:
≥ 99% (GC)
Synonym(s):
(Boc-amino)malonic acid diethyl ester, Diethyl 2-[N-(tert-butoxycarbonyl)amino]malonate
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Product Information

Diethyl (Boc-amino)malonate is a versatile compound widely utilized in organic synthesis and pharmaceutical research. This compound features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and reactivity, making it an ideal choice for various applications in peptide synthesis and drug development. Its unique structure allows for the introduction of amino acids and other functional groups, facilitating the creation of complex molecules. Researchers appreciate its role in the synthesis of bioactive compounds, where it serves as a key intermediate in the production of pharmaceuticals and agrochemicals.

In addition to its applications in synthetic chemistry, Diethyl (Boc-amino)malonate is recognized for its efficiency in generating diverse chemical libraries, which are essential for high-throughput screening in drug discovery. Its favorable properties, such as good solubility and ease of handling, make it a preferred choice for chemists looking to streamline their workflows. With its broad range of applications and significant advantages over similar compounds, Diethyl (Boc-amino)malonate stands out as a valuable tool for researchers and industry professionals alike.

Synonyms
(Boc-amino)malonic acid diethyl ester, Diethyl 2-[N-(tert-butoxycarbonyl)amino]malonate
CAS Number
102831-44-7
Purity
≥ 99% (GC)
Molecular Formula
C12H21NO6
Molecular Weight
275.3
MDL Number
MFCD00239423
PubChem ID
382219
Density
1.079 g/mL at 25 °C
Appearance
Colorless liquid
Boiling Point
218 °C
Refractive Index
n20/D 1.438
Conditions
Store at 0-8 °C
General Information
Synonyms
(Boc-amino)malonic acid diethyl ester, Diethyl 2-[N-(tert-butoxycarbonyl)amino]malonate
CAS Number
102831-44-7
Purity
≥ 99% (GC)
Molecular Formula
C12H21NO6
Molecular Weight
275.3
MDL Number
MFCD00239423
PubChem ID
382219
Density
1.079 g/mL at 25 °C
Appearance
Colorless liquid
Boiling Point
218 °C
Refractive Index
n20/D 1.438
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Diethyl (Boc-amino)malonate is widely utilized in research focused on:

  • Synthetic Organic Chemistry: This compound serves as a versatile building block in the synthesis of various pharmaceuticals and agrochemicals, allowing chemists to create complex molecules efficiently.
  • Peptide Synthesis: It is employed in the preparation of protected amino acids, which are crucial for peptide synthesis, making it easier to develop new therapeutic peptides.
  • Drug Development: Researchers use this compound to modify drug candidates, enhancing their bioavailability and stability, which is vital in the pharmaceutical industry.
  • Bioconjugation: Its reactive functional groups facilitate bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, which is important in targeted therapy.
  • Material Science: This chemical is also explored in the development of new materials, such as polymers, that require specific functional properties for applications in electronics and coatings.

Citations