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Catalog Number:
12908
CAS Number:
691-24-7
N,N'-Di-tert-butylcarbodiimide
Purity:
≥ 99% (GC)
Hazmat
Documents
$29.34 /1ML
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Product Information

N,N'-Di-tert-butylcarbodiimide is a versatile reagent widely utilized in organic synthesis, particularly in the formation of amides and esters. This compound is recognized for its ability to activate carboxylic acids, facilitating the coupling reactions essential in peptide synthesis and other complex organic transformations. Its unique structure, featuring two bulky tert-butyl groups, enhances its stability and reduces the likelihood of side reactions, making it a preferred choice for chemists seeking reliable results in their synthetic pathways.

In addition to its role in peptide coupling, N,N'-Di-tert-butylcarbodiimide is also employed in the preparation of various heterocycles and in the modification of biomolecules, showcasing its relevance in pharmaceutical and biotechnological applications. Researchers appreciate its efficiency and effectiveness, as it often leads to higher yields and purities compared to other coupling agents. This compound stands out for its user-friendly handling and compatibility with a wide range of functional groups, making it an essential tool in the arsenal of organic chemists.

CAS Number
691-24-7
Purity
≥ 99% (GC)
Molecular Formula
C9H18N2
Molecular Weight
154.26
MDL Number
MFCD00010231
PubChem ID
69650
Density
0.800
Appearance
Almost colorless clear liquid
Boiling Point
48 - 50 °C/12 mmHg
Refractive Index
1.428
Conditions
Store at RT
General Information
CAS Number
691-24-7
Purity
≥ 99% (GC)
Molecular Formula
C9H18N2
Molecular Weight
154.26
MDL Number
MFCD00010231
PubChem ID
69650
Density
0.800
Appearance
Almost colorless clear liquid
Boiling Point
48 - 50 °C/12 mmHg
Refractive Index
1.428
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N,N'-Di-tert-butylcarbodiimide is widely utilized in research focused on

  • Peptide Synthesis: This compound is a powerful coupling agent in the formation of peptide bonds, making it essential for synthesizing peptides in pharmaceutical research.
  • Organic Synthesis: It serves as a versatile reagent for various organic transformations, allowing chemists to create complex molecules efficiently.
  • Bioconjugation: The compound is used to link biomolecules, such as proteins and nucleic acids, which is crucial in developing targeted drug delivery systems.
  • Polymer Chemistry: It plays a role in the modification of polymers, enhancing their properties for applications in materials science and engineering.
  • Analytical Chemistry: N,N'-Di-tert-butylcarbodiimide is utilized in the preparation of samples for mass spectrometry, improving the accuracy of analytical results.

Citations