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Catalog Number:
12831
CAS Number:
106627-54-7
N-Hydroxysulfosuccinimide sodium salt
Purity:
≥ 99% (HPLC)
Synonym(s):
Hydroxy-2,5-dioxo-pyrrolidine-3-sulfonic-acid sodium salt, Sulfo-NHS
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$35.30 /1G
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Product Information

N-Hydroxysulfosuccinimide sodium salt is a versatile reagent widely utilized in biochemistry and molecular biology. This compound serves as an effective crosslinking agent, particularly in the modification of proteins and peptides, enhancing their stability and functionality. Its unique sulfonate group provides excellent solubility in aqueous solutions, making it ideal for various applications in enzymatic assays, protein labeling, and drug development. Researchers appreciate its ability to selectively modify amino groups, facilitating the study of protein interactions and dynamics.

In addition to its role in protein chemistry, N-Hydroxysulfosuccinimide sodium salt is also employed in the synthesis of bioconjugates, where it aids in the attachment of biomolecules to surfaces or other molecules. This property is particularly valuable in the development of biosensors and diagnostic tools, where precise biomolecule attachment is crucial for performance. With its reliable performance and ease of use, this compound stands out as a preferred choice for researchers seeking to enhance their experimental outcomes.

Synonyms
Hydroxy-2,5-dioxo-pyrrolidine-3-sulfonic-acid sodium salt, Sulfo-NHS
CAS Number
106627-54-7
Purity
≥ 99% (HPLC)
Molecular Formula
C4H4NNaO6S
Molecular Weight
217.13
MDL Number
MFCD00043100
PubChem ID
3520574
Melting Point
> 300 ºC
Appearance
Off-white to white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Hydroxy-2,5-dioxo-pyrrolidine-3-sulfonic-acid sodium salt, Sulfo-NHS
CAS Number
106627-54-7
Purity
≥ 99% (HPLC)
Molecular Formula
C4H4NNaO6S
Molecular Weight
217.13
MDL Number
MFCD00043100
PubChem ID
3520574
Melting Point
> 300 ºC
Appearance
Off-white to white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-Hydroxysulfosuccinimide sodium salt is widely utilized in research focused on:

  • Bioconjugation: This compound serves as an effective crosslinker for attaching proteins to surfaces or other biomolecules, enhancing the development of biosensors and diagnostic tools.
  • Protein Modification: It is commonly used to modify proteins for various applications, including drug delivery systems, where it helps improve stability and solubility.
  • Antibody Labeling: Researchers use this chemical for labeling antibodies in immunoassays, which is crucial for detecting specific proteins in complex samples.
  • Drug Development: In pharmaceutical research, it aids in the formulation of targeted therapies by facilitating the conjugation of drugs to carrier molecules, improving their efficacy.
  • Environmental Applications: It is also explored in environmental science for the development of sensors that detect pollutants, contributing to better monitoring of environmental health.

Citations