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Catalog Number:
12793
CAS Number:
114873-04-0
Boc-2,4-dichloro-L-phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Phe(2,4-DiCl)-OH, Boc-L-Phe(2,4-Cl2)-OH, (S-Boc-2-amino-3-(2,4-dichlorophenyl)propionic acid
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$93.14 /1G
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Product Information

Boc-2,4-dichloro-L-phenylalanine is a versatile amino acid derivative that serves as a valuable building block in peptide synthesis and medicinal chemistry. This compound is particularly recognized for its unique ability to introduce chlorinated aromatic groups into peptide structures, enhancing their biological activity and specificity. Its Boc (tert-butyloxycarbonyl) protecting group allows for easy manipulation during synthesis, making it an ideal choice for researchers looking to develop novel therapeutics or study protein interactions.

In pharmaceutical research, Boc-2,4-dichloro-L-phenylalanine has been utilized in the design of inhibitors targeting various enzymes and receptors, showcasing its potential in drug discovery. Additionally, its application in the synthesis of cyclic peptides has opened new avenues in the development of targeted therapies. With its favorable properties and functional versatility, this compound stands out as a key reagent for both academic and industrial applications, providing researchers with the tools necessary to innovate in the fields of biochemistry and pharmacology.

Synonyms
Boc-L-Phe(2,4-DiCl)-OH, Boc-L-Phe(2,4-Cl2)-OH, (S-Boc-2-amino-3-(2,4-dichlorophenyl)propionic acid
CAS Number
114873-04-0
Purity
≥ 99% (HPLC)
Molecular Formula
C14H17Cl2NO4
Molecular Weight
334.2
MDL Number
MFCD01862942
PubChem ID
4393347
Melting Point
134-139 °C
Appearance
Off-white powder
Optical Rotation
[a]D20 = -33 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Phe(2,4-DiCl)-OH, Boc-L-Phe(2,4-Cl2)-OH, (S-Boc-2-amino-3-(2,4-dichlorophenyl)propionic acid
CAS Number
114873-04-0
Purity
≥ 99% (HPLC)
Molecular Formula
C14H17Cl2NO4
Molecular Weight
334.2
MDL Number
MFCD01862942
PubChem ID
4393347
Melting Point
134-139 °C
Appearance
Off-white powder
Optical Rotation
[a]D20 = -33 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-2,4-dichloro-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of therapeutic agents and biologically active compounds.
  • Drug Development: Its unique structure allows researchers to explore new drug candidates, especially in the field of cancer research, where it can be used to design inhibitors targeting specific pathways.
  • Biochemical Studies: The compound is employed in studying protein interactions and enzyme activities, helping scientists understand biological processes at a molecular level.
  • Research on Amino Acid Analogues: It acts as a model compound for investigating the effects of amino acid modifications, providing insights into how structural changes influence biological activity.
  • Custom Synthesis: Due to its specific properties, it is often used in custom synthesis projects, enabling researchers to tailor compounds for specific applications in pharmaceuticals and biotechnology.

Citations