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Catalog Number:
12767
CAS Number:
203854-51-7
Fmoc-O-tert-butyl-L-ॆ-homoserine
Purity:
≥ 95% (Assay)
Synonym(s):
Fmoc-L-β-HomoSer(tBu)-OH
Documents
$80.30 /100MG
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Product Information

Fmoc-O-tert-butyl-L-b-homoserine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its tert-butyl ester enhances solubility and stability, making it an ideal choice for researchers aiming to streamline their synthesis processes. The unique structure of Fmoc-O-tert-butyl-L-b-homoserine allows for efficient incorporation into peptides, facilitating the development of bioactive compounds with potential therapeutic applications.

In addition to its role in peptide synthesis, Fmoc-O-tert-butyl-L-b-homoserine can also be employed in the design of novel drug candidates and in the study of protein interactions. Its ability to provide a stable and easily removable protecting group makes it a valuable tool for chemists and biochemists alike. With its practical applications in pharmaceuticals and biotechnology, this compound is an essential asset for professionals looking to enhance their research and development efforts.

Synonyms
Fmoc-L-β-HomoSer(tBu)-OH
CAS Number
203854-51-7
Purity
≥ 95% (Assay)
Molecular Formula
C23H27NO5
Molecular Weight
397.47
MDL Number
MFCD01862865
PubChem ID
4641408
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 25 ± 2 º (C=1 in DMF) [a]D20 = 15 ± 2 º (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-HomoSer(tBu)-OH
CAS Number
203854-51-7
Purity
≥ 95% (Assay)
Molecular Formula
C23H27NO5
Molecular Weight
397.47
MDL Number
MFCD01862865
PubChem ID
4641408
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 25 ± 2 º (C=1 in DMF) [a]D20 = 15 ± 2 º (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-tert-butyl-L-b-homoserine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others, which is crucial for creating complex peptide structures.
  • Drug Development: It is used in the development of pharmaceutical compounds, particularly in creating analogs of bioactive peptides that can lead to new therapeutic agents.
  • Bioconjugation: The compound facilitates bioconjugation processes, enabling researchers to attach biomolecules to surfaces or other molecules, enhancing the functionality of drugs and diagnostics.
  • Research in Protein Engineering: It aids in the design of novel proteins with specific functions, allowing scientists to explore new biochemical pathways and therapeutic targets.
  • Analytical Chemistry: The compound is employed in various analytical techniques, including chromatography and mass spectrometry, to improve the separation and identification of complex mixtures.

Citations