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Catalog Number:
12766
CAS Number:
353245-99-5
Fmoc-O-tert-butyl-L-ॆ-homothreonine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-β-HomoThr(tBu)-OH, (3R,4R)-4-tert-Butoxy-3-(Fmoc-amino)pentanoic acid
Documents
$65.00 /100MG
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Product Information

Fmoc-O-tert-butyl-L-b-homothreonine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of complex peptides. Its tert-butyl group enhances solubility and stability, making it an ideal choice for researchers working on solid-phase peptide synthesis. The unique structure of Fmoc-O-tert-butyl-L-b-homothreonine allows for efficient coupling reactions, facilitating the formation of peptides with high purity and yield.

In addition to its applications in peptide synthesis, this compound is also explored in the development of novel therapeutics, particularly in the fields of oncology and immunology. Researchers appreciate its ability to provide a stable and versatile building block for creating bioactive peptides. With its favorable properties and practical applications, Fmoc-O-tert-butyl-L-b-homothreonine stands out as a crucial component in the toolkit of peptide chemists and pharmaceutical developers.

Synonyms
Fmoc-L-β-HomoThr(tBu)-OH, (3R,4R)-4-tert-Butoxy-3-(Fmoc-amino)pentanoic acid
CAS Number
353245-99-5
Purity
≥ 98% (HPLC)
Molecular Formula
C24H29NO5
Molecular Weight
411.5
MDL Number
MFCD01863057
PubChem ID
4640570
Appearance
White to light yellow glassy solid
Optical Rotation
[a]D25 = 16 ± 2 º (C=1 in DMF) [a]D20 = 6 ± 1 º (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-HomoThr(tBu)-OH, (3R,4R)-4-tert-Butoxy-3-(Fmoc-amino)pentanoic acid
CAS Number
353245-99-5
Purity
≥ 98% (HPLC)
Molecular Formula
C24H29NO5
Molecular Weight
411.5
MDL Number
MFCD01863057
PubChem ID
4640570
Appearance
White to light yellow glassy solid
Optical Rotation
[a]D25 = 16 ± 2 º (C=1 in DMF) [a]D20 = 6 ± 1 º (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-tert-butyl-L-b-homothreonine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences with high purity and yield.
  • Drug Development: It is used in the development of pharmaceutical compounds, particularly in the design of peptide-based drugs, enhancing their stability and bioavailability.
  • Bioconjugation: The chemical is valuable for bioconjugation applications, where it helps in attaching biomolecules to surfaces or other molecules, improving the efficacy of therapeutic agents.
  • Research in Proteomics: It plays a significant role in proteomics studies, aiding in the identification and characterization of proteins through advanced labeling techniques.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis services using this compound, catering to specific research needs and providing tailored solutions for scientists and researchers.

Citations