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Catalog Number:
12765
CAS Number:
353245-98-4
Fmoc-L-ॆ-homotryptophan
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-β-HomoTrp-OH, (S-3-(Fmoc-amino)-4-(3-indolyl)butyric acid
Documents
$58.39 /100MG
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Product Information

Fmoc-L-b-homotryptophan is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which facilitates the selective coupling of amino acids in solid-phase peptide synthesis, making it an essential building block for researchers in the field of medicinal chemistry. Its unique structure, which includes an indole side chain, enhances its compatibility with various coupling reagents, allowing for efficient synthesis of complex peptides.

In addition to its role in peptide synthesis, Fmoc-L-b-homotryptophan has potential applications in the development of novel therapeutic agents, particularly in the design of bioactive peptides that target specific biological pathways. Researchers appreciate its stability and ease of handling, which contribute to streamlined workflows in laboratory settings. With its ability to enhance the properties of synthesized peptides, this compound stands out as a valuable resource for professionals aiming to innovate in drug discovery and development.

Synonyms
Fmoc-L-β-HomoTrp-OH, (S-3-(Fmoc-amino)-4-(3-indolyl)butyric acid
CAS Number
353245-98-4
Purity
≥ 98% (HPLC)
Molecular Formula
C27H24N2O4
Molecular Weight
440.5
MDL Number
MFCD01863056
PubChem ID
5061202
Appearance
White to greyish powder
Optical Rotation
[a]D20 = -26 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-β-HomoTrp-OH, (S-3-(Fmoc-amino)-4-(3-indolyl)butyric acid
CAS Number
353245-98-4
Purity
≥ 98% (HPLC)
Molecular Formula
C27H24N2O4
Molecular Weight
440.5
MDL Number
MFCD01863056
PubChem ID
5061202
Appearance
White to greyish powder
Optical Rotation
[a]D20 = -26 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-b-homotryptophan is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of therapeutic proteins and biologically active peptides.
  • Drug Development: Researchers leverage its unique properties to design and optimize drug candidates, especially those targeting neurological disorders, due to its structural similarity to tryptophan.
  • Bioconjugation: It is used in bioconjugation processes, allowing for the attachment of various biomolecules to peptides, enhancing their functionality and targeting capabilities in drug delivery systems.
  • Fluorescent Probes: The compound can be incorporated into fluorescent probes, facilitating the study of protein interactions and cellular processes in live cells.
  • Research in Neuroscience: Its structural characteristics make it valuable in studies related to serotonin receptors and other neurobiological pathways, aiding in the understanding of mood disorders.

Citations