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Catalog Number:
12749
CAS Number:
51871-62-6
Boc-L-β-homophenylalanine
Purity:
≥ 98%
Synonym(s):
Boc-L-β-HomoPhe-OH, (S-Boc-3-amino-4-phenylbutyric acid
Documents
$86.23 /250MG
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Product Information

Boc-L-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an excellent choice for researchers looking to streamline their synthesis processes. Its unique structure allows for the incorporation of bulky side chains, which can significantly influence the biological activity of peptides, thus providing valuable insights into structure-activity relationships in medicinal chemistry.

In practical applications, Boc-L-b-homophenylalanine is particularly beneficial in the design of peptide-based therapeutics, where the modification of amino acid sequences can lead to improved efficacy and selectivity. Its use in combinatorial chemistry and high-throughput screening has opened new avenues for drug discovery, enabling the rapid identification of lead compounds. Researchers appreciate its compatibility with various coupling reagents and methods, making it a reliable choice for both academic and industrial applications.

Synonyms
Boc-L-β-HomoPhe-OH, (S-Boc-3-amino-4-phenylbutyric acid
CAS Number
51871-62-6
Purity
≥ 98%
Molecular Formula
C15H21NO4
Molecular Weight
279.34
MDL Number
MFCD01076271
PubChem ID
4991364
Melting Point
100-104 ?C
Appearance
White to off-white powder
Optical Rotation
-19.0±2° (c= 1% dichloromethane)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-β-HomoPhe-OH, (S-Boc-3-amino-4-phenylbutyric acid
CAS Number
51871-62-6
Purity
≥ 98%
Molecular Formula
C15H21NO4
Molecular Weight
279.34
MDL Number
MFCD01076271
PubChem ID
4991364
Melting Point
100-104 ?C
Appearance
White to off-white powder
Optical Rotation
-19.0±2° (c= 1% dichloromethane)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of therapeutic agents and biologically active compounds.
  • Drug Development: It plays a significant role in the pharmaceutical industry, aiding in the design of new drugs that target specific biological pathways, enhancing efficacy and reducing side effects.
  • Protein Engineering: Researchers use it to modify proteins, allowing for the creation of proteins with improved stability and functionality, which is crucial in biotechnology applications.
  • Bioconjugation: The compound is used in bioconjugation processes, linking biomolecules to drugs or imaging agents, thereby improving the delivery and targeting of therapeutics.
  • Research in Neuroscience: It is employed in studies related to neurotransmitter functions, helping scientists understand the role of amino acids in brain chemistry and potential treatments for neurological disorders.

Citations