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Catalog Number:
12744
CAS Number:
193954-28-8
Fmoc-L-β-homophenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-β-HomoPhe-OH, (S)-Fmoc-3-amino-4-phenylbutyric acid
Documents
$79.22 /250MG
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Product Information

Fmoc-L-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which enhances its stability and solubility, making it an ideal choice for solid-phase peptide synthesis. Researchers appreciate its ability to facilitate the formation of complex peptides while maintaining high purity and yield. The unique structure of Fmoc-L-b-homophenylalanine allows for the introduction of phenyl groups into peptides, which can significantly influence their biological activity and interactions.

In pharmaceutical research, this compound is particularly valuable for developing peptide-based therapeutics, including those targeting specific receptors or enzymes. Its application extends to the synthesis of peptide libraries for drug discovery, where the ability to modify side chains can lead to the identification of novel bioactive compounds. With its favorable properties and practical applications, Fmoc-L-b-homophenylalanine stands out as a crucial building block in modern peptide chemistry.

Synonyms
Fmoc-L-β-HomoPhe-OH, (S)-Fmoc-3-amino-4-phenylbutyric acid
CAS Number
193954-28-8
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD01863055
PubChem ID
4547493
Appearance
White powder
Optical Rotation
[a]D25 = -14.5 + 2 (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-HomoPhe-OH, (S)-Fmoc-3-amino-4-phenylbutyric acid
CAS Number
193954-28-8
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD01863055
PubChem ID
4547493
Appearance
White powder
Optical Rotation
[a]D25 = -14.5 + 2 (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity.
  • Drug Development: It plays a significant role in drug discovery, especially in developing peptide-based therapeutics, which can target specific biological pathways more effectively than traditional small molecules.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach peptides to proteins or other biomolecules, enhancing their stability and functionality in therapeutic applications.
  • Research in Neuroscience: Fmoc-L-b-homophenylalanine is utilized in studies related to neurotransmitter systems, aiding in the development of compounds that can modulate synaptic activity.
  • Custom Peptide Libraries: It is instrumental in creating diverse peptide libraries for screening in various biological assays, facilitating the discovery of novel bioactive compounds.