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Catalog Number:
12549
CAS Number:
122194-07-4
Dimethyl-N,N-diisopropylphosphoramidite
Purity:
≥ 97% (31P NMR)
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Product Information

Dimethyl-N,N-diisopropylphosphoramidite is a versatile chemical compound widely utilized in the field of organic synthesis, particularly in the preparation of phosphoramidite reagents for oligonucleotide synthesis. This compound serves as a key building block in the production of phosphorothioate and phosphodiester linkages, which are essential for the development of therapeutic oligonucleotides and nucleic acid-based drugs. Its unique structure allows for enhanced stability and reactivity, making it an ideal choice for researchers looking to streamline their synthetic processes.

In addition to its applications in nucleic acid chemistry, Dimethyl-N,N-diisopropylphosphoramidite is also employed in various fields such as agrochemicals and pharmaceuticals, where it contributes to the synthesis of complex molecules. Its ability to facilitate efficient coupling reactions and its compatibility with a range of functional groups make it a valuable asset in both academic and industrial laboratories. Researchers and professionals can benefit from its high purity and reliability, ensuring consistent results in their experiments and formulations.

CAS Number
122194-07-4
Purity
≥ 97% (31P NMR)
Molecular Formula
C8H20NO2P
Molecular Weight
193.2
MDL Number
MFCD00153505
PubChem ID
5171659
Density
0.840 g/mL at 20 °C (Lit.)
Appearance
Clear, colorless oily liquid
Conditions
Store at 0 - 8 °C under Nitrogen.
General Information
CAS Number
122194-07-4
Purity
≥ 97% (31P NMR)
Molecular Formula
C8H20NO2P
Molecular Weight
193.2
MDL Number
MFCD00153505
PubChem ID
5171659
Density
0.840 g/mL at 20 °C (Lit.)
Appearance
Clear, colorless oily liquid
Conditions
Store at 0 - 8 °C under Nitrogen.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Dimethyl-N,N-diisopropylphosphoramidite is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound is a key reagent in the synthesis of oligonucleotides, which are essential for genetic research, diagnostics, and therapeutic applications.
  • Phosphoramidite Chemistry: It serves as a versatile building block in the development of phosphoramidite derivatives, enhancing the efficiency of chemical reactions in organic synthesis.
  • Drug Development: Its unique properties allow for the modification of pharmaceutical compounds, aiding in the design of more effective drugs with improved bioavailability.
  • Bioconjugation: The compound is used in creating bioconjugates, which are important for targeted drug delivery systems and in the development of diagnostic tools.
  • Research in Material Science: It plays a role in the synthesis of new materials, including polymers and nanomaterials, contributing to advancements in various industrial applications.

Citations