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Catalog Number:
12435
CAS Number:
204251-86-5
Fmoc-D-glutamic acid α-allyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Glu-OAll
Documents
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Product Information

Fmoc-D-glutamic acid a-allyl ester is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which provides stability during the synthesis process while allowing for easy deprotection when needed. Its unique allyl ester functionality enhances its reactivity, making it an excellent choice for coupling reactions in the formation of complex peptides. Researchers and industry professionals appreciate its role in developing bioactive peptides, pharmaceuticals, and other biologically relevant compounds.

In addition to its utility in peptide synthesis, Fmoc-D-glutamic acid a-allyl ester is also employed in various applications within the fields of drug discovery and materials science. Its ability to facilitate the formation of peptide bonds while maintaining structural integrity makes it a valuable tool for creating novel therapeutic agents. The compound's favorable properties, such as solubility and stability, further enhance its appeal for researchers seeking reliable building blocks in their synthetic pathways.

Synonyms
Fmoc-D-Glu-OAll
CAS Number
204251-86-5
Purity
≥ 98% (HPLC)
Molecular Formula
C23H23NO6
Molecular Weight
409.43
MDL Number
MFCD01074691
PubChem ID
3425156
Melting Point
111 - 128 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 18 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Glu-OAll
CAS Number
204251-86-5
Purity
≥ 98% (HPLC)
Molecular Formula
C23H23NO6
Molecular Weight
409.43
MDL Number
MFCD01074691
PubChem ID
3425156
Melting Point
111 - 128 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 18 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-glutamic acid a-allyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially those targeting neurological disorders, due to its ability to mimic natural amino acids.
  • Bioconjugation: The allyl ester group enables selective reactions for bioconjugation, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies.
  • Research in Neuroscience: It is used in studies related to neurotransmitter functions and signaling pathways, providing insights into brain function and potential treatments for cognitive disorders.
  • Material Science: The compound can be incorporated into polymer matrices to enhance material properties, making it useful in developing advanced materials for various applications.

Citations