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Catalog Number:
12407
CAS Number:
185031-78-1
Nα-Fmoc-Nγ-xanthyl-L-asparagine
Purity:
≥ 96% (HPLC)
Synonym(s):
Fmoc-L-Asn(Xan)-OH
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Product Information

Na-Fmoc-Ng-xanthyl-L-asparagine is a specialized amino acid derivative that plays a pivotal role in peptide synthesis and bioconjugation applications. This compound is particularly valued in the field of medicinal chemistry and biochemistry for its ability to facilitate the formation of complex peptide structures. The Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection under mild conditions, making it an ideal choice for researchers looking to synthesize peptides with high specificity and yield. Additionally, the xanthyl group enhances the compound's solubility and stability, which is crucial for various biochemical applications.

This compound is widely utilized in the development of peptide-based therapeutics, where precise control over amino acid sequences is essential. Its unique properties make it suitable for applications in drug discovery, particularly in the design of inhibitors and biologically active peptides. Researchers appreciate Na-Fmoc-Ng-xanthyl-L-asparagine for its compatibility with automated peptide synthesizers, streamlining the synthesis process and improving efficiency. With its robust performance in peptide synthesis, this compound stands out as a valuable tool for professionals in the pharmaceutical and biotechnology sectors.

Synonyms
Fmoc-L-Asn(Xan)-OH
CAS Number
185031-78-1
Purity
≥ 96% (HPLC)
Molecular Formula
C32H26N2O6
Molecular Weight
534.54
MDL Number
MFCD07366857
PubChem ID
137704819
Melting Point
190 - 202 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -3 to -6 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Asn(Xan)-OH
CAS Number
185031-78-1
Purity
≥ 96% (HPLC)
Molecular Formula
C32H26N2O6
Molecular Weight
534.54
MDL Number
MFCD07366857
PubChem ID
137704819
Melting Point
190 - 202 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -3 to -6 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ng-xanthyl-L-asparagine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in peptide synthesis, allowing for the selective modification of amino acids. Its stability under various reaction conditions makes it a preferred choice for chemists working on complex peptide sequences.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. Its unique structure can enhance the bioavailability and efficacy of therapeutic peptides, making it valuable in the development of new medications.
  • Bioconjugation: The chemical is employed in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules. This application is crucial in creating targeted drug delivery systems and diagnostic tools.
  • Fluorescent Probes: Due to its xanthene moiety, it can be used in developing fluorescent probes for biological imaging. This application is particularly beneficial in cellular studies, allowing researchers to visualize cellular processes in real-time.
  • Research in Protein Engineering: It plays a significant role in protein engineering, aiding in the design of proteins with enhanced stability and functionality. This is particularly important in fields like biotechnology and synthetic biology.

Citations