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Catalog Number:
12146
CAS Number:
84025-81-0
R-(-)-2-(Methoxymethyl)pyrrolidine
Purity:
≥ 99.5% (GC, Chiral purity)
Synonym(s):
O-Methyl-D-Prolinol
Hazmat
Documents
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Product Information

(R)-(-)-2-(Methoxymethyl)pyrrolidine is a versatile chiral building block widely utilized in the synthesis of various pharmaceuticals and agrochemicals. This compound is recognized for its unique ability to enhance the efficacy of active pharmaceutical ingredients (APIs) due to its chiral nature, making it an essential component in the development of enantiomerically pure compounds. Its methoxymethyl group provides additional reactivity, allowing for diverse functionalization opportunities in organic synthesis. Researchers and industry professionals leverage this compound in the creation of novel therapeutic agents, particularly in the fields of central nervous system disorders and anti-cancer drugs, where precise stereochemistry is crucial for biological activity.

The compound's favorable properties, including its moderate boiling point and solubility in organic solvents, facilitate its use in various chemical reactions, such as nucleophilic substitutions and coupling reactions. This makes (R)-(-)-2-(Methoxymethyl)pyrrolidine an attractive choice for those looking to streamline their synthetic pathways while ensuring high yields and purity. Its application in asymmetric synthesis further underscores its importance in modern chemistry, providing a reliable route to complex molecular architectures that are vital in drug development.

Synonyms
O-Methyl-D-Prolinol
CAS Number
84025-81-0
Purity
≥ 99.5% (GC, Chiral purity)
Molecular Formula
C6H13NO
Molecular Weight
115.16
MDL Number
MFCD00066219
PubChem ID
143953
Density
0.932 g/mL at 20 ?C
Appearance
Colorless liquid
Refractive Index
n20/D 1.446
Conditions
Store at 0-8 °C
General Information
Synonyms
O-Methyl-D-Prolinol
CAS Number
84025-81-0
Purity
≥ 99.5% (GC, Chiral purity)
Molecular Formula
C6H13NO
Molecular Weight
115.16
MDL Number
MFCD00066219
PubChem ID
143953
Density
0.932 g/mL at 20 ?C
Appearance
Colorless liquid
Refractive Index
n20/D 1.446
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(-)-2-(Methoxymethyl)pyrrolidine is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Chemical Synthesis: It is employed in the synthesis of complex organic molecules, facilitating the creation of compounds with specific functionalities that are crucial in medicinal chemistry.
  • Chiral Catalysis: As a chiral building block, it plays a significant role in asymmetric synthesis, allowing researchers to create enantiomerically pure compounds, which are essential in the pharmaceutical industry.
  • Biochemical Research: The compound is used in studies related to neurotransmitter systems, helping scientists understand mechanisms of action for various drugs and their effects on the brain.
  • Material Science: It finds applications in the development of novel materials, including polymers and coatings, due to its unique chemical properties that enhance material performance.

Citations