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Catalog Number:
11888
CAS Number:
28307-08-6
Boc-L-threonine 4-nitrophenyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Thr-ONp
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Product Information

Boc-L-threonine 4-nitrophenyl ester is a valuable compound widely utilized in peptide synthesis and pharmaceutical research. This derivative of threonine features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and facilitates the formation of peptide bonds. Its unique structure allows for selective reactions, making it an essential building block in the development of bioactive peptides and therapeutic agents. Researchers appreciate its role in the synthesis of complex molecules, particularly in the fields of drug discovery and development, where precision and efficiency are paramount.

In addition to its applications in peptide synthesis, Boc-L-threonine 4-nitrophenyl ester serves as a useful intermediate in the production of various pharmaceuticals, agrochemicals, and fine chemicals. Its ability to undergo specific transformations while maintaining structural integrity makes it a preferred choice for chemists looking to streamline their synthetic pathways. With its favorable properties and versatility, this compound is an indispensable tool for professionals aiming to innovate and enhance their research outcomes.

Synonyms
Boc-L-Thr-ONp
CAS Number
28307-08-6
Purity
≥ 98% (HPLC)
Molecular Formula
C15H20N2O7
Molecular Weight
340.33
MDL Number
MFCD00190835
PubChem ID
91977066
Melting Point
59-66 °C
Appearance
Pale yellow powder
Optical Rotation
[α]D20 = -12 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Thr-ONp
CAS Number
28307-08-6
Purity
≥ 98% (HPLC)
Molecular Formula
C15H20N2O7
Molecular Weight
340.33
MDL Number
MFCD00190835
PubChem ID
91977066
Melting Point
59-66 °C
Appearance
Pale yellow powder
Optical Rotation
[α]D20 = -12 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-threonine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, facilitating the incorporation of threonine residues, which are essential for various biological functions.
  • Drug Development: It plays a crucial role in the design of pharmaceuticals, particularly in creating compounds that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The ester functionality allows for easy conjugation with other biomolecules, making it useful in developing targeted drug delivery systems and diagnostic agents.
  • Research in Protein Engineering: It is employed in modifying proteins to study structure-function relationships, aiding researchers in understanding protein interactions and stability.
  • Analytical Chemistry: This compound can be used as a standard in analytical methods to quantify threonine derivatives, ensuring accuracy in various biochemical assays.

Citations