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Catalog Number:
11887
CAS Number:
79479-07-5
Boc-L-threonine methyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Thr-OMe
Documents
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Product Information

Boc-L-threonine methyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and facilitates the selective functionalization of the amino acid during synthesis. Its unique structure allows for the incorporation of threonine into peptides, making it invaluable in the development of biologically active compounds, including therapeutics and research reagents.

Researchers appreciate Boc-L-threonine methyl ester for its ease of use in solid-phase peptide synthesis, where it can be employed to create complex peptide sequences with high purity and yield. This compound is particularly beneficial in the synthesis of peptides that require specific stereochemistry, as it maintains the integrity of the threonine residue throughout the process. Its applications extend to the production of peptide-based drugs and the study of protein interactions, making it a crucial tool for chemists and biochemists alike.

Synonyms
Boc-L-Thr-OMe
CAS Number
79479-07-5
Purity
≥ 98% (HPLC)
Molecular Formula
C10H19NO5
Molecular Weight
233.26
MDL Number
MFCD00270479
PubChem ID
4351132
Appearance
Light yellow transparent oil
Optical Rotation
[a]D20 = -17 ± 2º (C=2 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Thr-OMe
CAS Number
79479-07-5
Purity
≥ 98% (HPLC)
Molecular Formula
C10H19NO5
Molecular Weight
233.26
MDL Number
MFCD00270479
PubChem ID
4351132
Appearance
Light yellow transparent oil
Optical Rotation
[a]D20 = -17 ± 2º (C=2 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-threonine methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those that require threonine residues, enhancing the efficiency of creating complex peptide structures.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing new drugs, especially in creating therapeutics that target specific biological pathways involving amino acids.
  • Biotechnology: In biotechnological applications, it is used in the production of recombinant proteins, aiding in the development of biologics that can treat various diseases.
  • Research on Protein Folding: The compound is valuable in studies related to protein folding and stability, helping researchers understand how proteins achieve their functional forms.
  • Modification of Natural Products: It is used to modify natural products, allowing chemists to enhance the properties of existing compounds for better efficacy in applications such as agriculture and medicine.

Citations