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Catalog Number:
11882
CAS Number:
59936-29-7
Boc-L-proline methyl ester
Purity:
≥ 99% (GC)
Synonym(s):
Boc-L-Pro-OMe, (S)-Boc-pyrrolidine-2-carboxylic acid methyl ester
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$32.75 /5G
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Product Information

Boc-L-proline methyl ester is a versatile compound widely utilized in organic synthesis and pharmaceutical research. This protected amino acid derivative features a tert-butoxycarbonyl (Boc) group, which enhances its stability and solubility, making it an ideal choice for peptide synthesis and drug development. Its unique structure allows for selective reactions, facilitating the formation of complex molecules in a streamlined manner. Researchers often employ Boc-L-proline methyl ester in the synthesis of cyclic peptides and other bioactive compounds, leveraging its ability to serve as a chiral building block.

The compound's favorable properties, such as its ease of handling and compatibility with various reaction conditions, make it a preferred choice in laboratories focused on medicinal chemistry and biochemistry. Its application extends to the development of novel therapeutics, where it plays a crucial role in creating compounds with enhanced biological activity. With its proven track record in facilitating efficient synthesis, Boc-L-proline methyl ester stands out as a valuable asset for professionals aiming to innovate in drug discovery and development.

Synonyms
Boc-L-Pro-OMe, (S)-Boc-pyrrolidine-2-carboxylic acid methyl ester
CAS Number
59936-29-7
Purity
≥ 99% (GC)
Molecular Formula
C11H19NO4
Molecular Weight
229.3
MDL Number
MFCD01075092
PubChem ID
394147
Appearance
Pale yellow liquid
Optical Rotation
[a]D20 = -59 ± 2 ° (C=1 in Chloroform)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Pro-OMe, (S)-Boc-pyrrolidine-2-carboxylic acid methyl ester
CAS Number
59936-29-7
Purity
≥ 99% (GC)
Molecular Formula
C11H19NO4
Molecular Weight
229.3
MDL Number
MFCD01075092
PubChem ID
394147
Appearance
Pale yellow liquid
Optical Rotation
[a]D20 = -59 ± 2 ° (C=1 in Chloroform)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-proline methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the formation of proline-containing sequences, enhancing the structural diversity of peptides.
  • Drug Development: It is used in the pharmaceutical industry for the development of proline-based drugs, which can have improved bioactivity and stability compared to other amino acid derivatives.
  • Bioconjugation: Researchers employ this chemical in bioconjugation processes, allowing for the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Material Science: It finds applications in the development of novel materials, particularly in creating polymers that require specific mechanical properties and functionalities.
  • Research in Enzyme Inhibition: The compound is also explored in studies aimed at understanding enzyme mechanisms, providing insights that can lead to the design of effective inhibitors.

Citations