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Catalog Number:
11867
CAS Number:
77611-37-1
Boc-L-6-hydroxynorleucine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Nle(6-OH)-OH, (S-Nα-Boc-2-amino-6-hydroxyhexanoic acid
Documents
$113.87 /1G
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Product Information

Boc-L-6-hydroxynorleucine is a valuable amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for researchers working on complex peptide sequences. Its unique hydroxyl group at the 6-position allows for further functionalization, enabling the development of novel therapeutic agents and bioactive peptides.

In the pharmaceutical industry, Boc-L-6-hydroxynorleucine serves as a crucial building block for the synthesis of peptides that can target specific biological pathways, offering potential applications in drug development and therapeutic interventions. Its compatibility with various coupling reagents and methodologies makes it a versatile tool for chemists and researchers. With its ability to facilitate the creation of tailored peptides, this compound stands out as a key player in advancing peptide-based therapies and enhancing drug efficacy.

Synonyms
Boc-L-Nle(6-OH)-OH, (S-Nα-Boc-2-amino-6-hydroxyhexanoic acid
CAS Number
77611-37-1
Purity
≥ 99% (HPLC)
Molecular Formula
C11H21NO5
Molecular Weight
247.3
MDL Number
MFCD01862292
PubChem ID
18329258
Melting Point
108-119 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -6.0 to -8.0º (C=7.3 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Nle(6-OH)-OH, (S-Nα-Boc-2-amino-6-hydroxyhexanoic acid
CAS Number
77611-37-1
Purity
≥ 99% (HPLC)
Molecular Formula
C11H21NO5
Molecular Weight
247.3
MDL Number
MFCD01862292
PubChem ID
18329258
Melting Point
108-119 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -6.0 to -8.0º (C=7.3 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-6-hydroxynorleucine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of biologically active compounds and pharmaceuticals.
  • Drug Development: It plays a crucial role in the design of new drugs, especially those targeting specific receptors or enzymes, enhancing the efficacy and selectivity of therapeutic agents.
  • Research in Neuroscience: The compound is used in studies related to neurotransmitter systems, aiding in the understanding of neurological disorders and potential treatments.
  • Bioconjugation Techniques: Boc-L-6-hydroxynorleucine is employed in bioconjugation processes, allowing for the attachment of biomolecules to surfaces or other compounds, which is essential in diagnostics and targeted therapies.
  • Protein Engineering: It is utilized in the modification of proteins to enhance their stability and functionality, which is particularly beneficial in biotechnology and therapeutic applications.

Citations