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Catalog Number:
11832
CAS Number:
85546-27-6
Boc-D-alanine-4-nitrophenyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-D-Ala-ONp
Documents
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Product Information

Boc-D-alanine-4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal choice for the synthesis of various bioactive peptides. Its unique 4-nitrophenyl ester functionality allows for selective cleavage under mild conditions, facilitating the release of the active D-alanine moiety. Researchers appreciate its application in the development of peptide-based drugs, where precise control over amino acid sequences is crucial.

In addition to its role in peptide synthesis, Boc-D-alanine-4-nitrophenyl ester serves as a valuable building block in the design of enzyme inhibitors and other therapeutic agents. Its compatibility with various coupling reagents and reaction conditions makes it a preferred choice for chemists aiming to streamline their synthetic pathways. The compound's favorable properties, such as high purity and stability, further enhance its appeal in both academic and industrial settings, ensuring reliable results in complex synthesis projects.

Synonyms
Boc-D-Ala-ONp
CAS Number
85546-27-6
Purity
≥ 99% (HPLC)
Molecular Formula
C14H18N2O6
Molecular Weight
310.31
MDL Number
MFCD01862290
PubChem ID
102826
Melting Point
144-152 °C
Optical Rotation
[α]D = +56 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-D-Ala-ONp
CAS Number
85546-27-6
Purity
≥ 99% (HPLC)
Molecular Formula
C14H18N2O6
Molecular Weight
310.31
MDL Number
MFCD01862290
PubChem ID
102826
Melting Point
144-152 °C
Optical Rotation
[α]D = +56 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-alanine-4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds.
  • Drug Development: It is used in the design of prodrugs, enhancing the bioavailability of certain medications by modifying their chemical properties for better absorption in the body.
  • Bioconjugation: The compound is valuable in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in diagnostics and therapeutic applications.
  • Research in Enzyme Inhibition: It plays a role in studying enzyme mechanisms, particularly in understanding how certain enzymes can be inhibited, which is important in drug discovery.
  • Analytical Chemistry: Boc-D-alanine-4-nitrophenyl ester is utilized in analytical methods to quantify amino acids and peptides, aiding researchers in characterizing complex biological samples.

Citations