Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
11630
CAS Number:
202920-22-7
Nα-Fmoc-Nim-methyl-L-histidine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-His(1-Me)-OH
Documents
$186.78 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Na-Fmoc-Nim-methyl-L-histidine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of the amino group during the synthesis of peptides. Its unique structure, incorporating a methylimidazole side chain, enhances its stability and solubility, making it an excellent choice for researchers focused on developing complex peptide sequences.

In the pharmaceutical industry, Na-Fmoc-Nim-methyl-L-histidine is particularly valuable for the synthesis of bioactive peptides that can serve as potential therapeutics. Its ability to facilitate the introduction of histidine residues into peptide chains allows for the exploration of new drug candidates with improved efficacy and specificity. Additionally, this compound's favorable properties enable its use in various applications, including the development of diagnostic agents and targeted delivery systems. Researchers can leverage its unique features to enhance the performance of their peptide-based projects, making it a critical tool in modern biochemistry and medicinal chemistry.

Synonyms
Fmoc-L-His(1-Me)-OH
CAS Number
202920-22-7
Purity
≥ 99% (HPLC)
Molecular Formula
C22H21N3O4
Molecular Weight
391.43
MDL Number
MFCD02259495
PubChem ID
68763713
Melting Point
135 - 136 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = - 9.0 ± 1 ° (C=1 in 2N HCl)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-His(1-Me)-OH
CAS Number
202920-22-7
Purity
≥ 99% (HPLC)
Molecular Formula
C22H21N3O4
Molecular Weight
391.43
MDL Number
MFCD02259495
PubChem ID
68763713
Melting Point
135 - 136 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = - 9.0 ± 1 ° (C=1 in 2N HCl)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nim-methyl-L-histidine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex structures with high purity.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing peptide-based drugs, especially those targeting specific receptors due to its unique side chain properties.
  • Bioconjugation: The chemical is used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted therapies and diagnostics.
  • Research in Protein Engineering: Researchers utilize this compound to modify proteins, enhancing their stability and activity, which is vital for developing new biocatalysts or therapeutic proteins.
  • Analytical Chemistry: It is employed in analytical methods to study protein interactions and dynamics, providing insights into biological processes and aiding in the design of new experiments.

Citations