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Catalog Number:
11338
CAS Number:
57519-09-2
H-His(1-Me)-OMe·HCl
Synonym(s):
L-His(Nim-Me)-OMe·HCl
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$127.79 /100MG
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Product Information

H-His(1-Me)-OMe·HCl, also known as methyl (2S)-2-amino-3-(1-methylimidazol-4-yl)propanoate, is a specialized amino acid derivative that plays a crucial role in biochemical research and pharmaceutical applications. This compound is particularly valued for its ability to serve as a building block in peptide synthesis, facilitating the development of bioactive peptides and proteins. Its unique structure, featuring a methylated imidazole side chain, enhances its stability and solubility, making it an ideal candidate for various formulations in drug development and therapeutic research.

Researchers and industry professionals utilize H-His(1-Me)-OMe·HCl in the synthesis of peptide-based drugs, where it can contribute to improved efficacy and bioavailability. Its application extends to the study of enzyme interactions and receptor binding, providing insights into metabolic pathways and potential therapeutic targets. The compound's favorable properties, such as its compatibility with various solvents and ease of incorporation into peptide sequences, make it a preferred choice for laboratories focused on innovative drug design and development.

Synonyms
L-His(Nim-Me)-OMe·HCl
CAS Number
57519-09-2
Molecular Formula
C8H13N3O2·HCl
Molecular Weight
219.67
MDL Number
MFCD00237978
PubChem ID
11693534
Melting Point
205-209 ºC
Appearance
Off-white powder
Optical Rotation
[a]D24 = +13.0 ± 2º (C=1% in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
L-His(Nim-Me)-OMe·HCl
CAS Number
57519-09-2
Molecular Formula
C8H13N3O2·HCl
Molecular Weight
219.67
MDL Number
MFCD00237978
PubChem ID
11693534
Melting Point
205-209 ºC
Appearance
Off-white powder
Optical Rotation
[a]D24 = +13.0 ± 2º (C=1% in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

H-His(1-Me)-OMe·HCl is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those that require histidine derivatives, enhancing the efficiency of creating complex biomolecules.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing drugs that target specific biological pathways, particularly in cancer and metabolic disorders.
  • Bioconjugation: Researchers use it for bioconjugation processes, allowing for the attachment of therapeutic agents to antibodies or other proteins, improving targeted delivery in treatments.
  • Research in Enzyme Activity: The compound is valuable in studying enzyme mechanisms and activities, particularly those involving histidine residues, providing insights into biochemical processes.
  • Diagnostic Applications: It is also applied in the development of diagnostic tools, especially in assays that require specific binding interactions, enhancing sensitivity and specificity.

Citations