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Catalog Number:
11334
CAS Number:
200871-52-9
Boc-D-His(1-Me)-OH
Purity:
≥ 99% (TLC)
Synonym(s):
Boc-D-His(Nim-Me)-OH
Documents
$156.00 /100MG
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Product Information

Boc-D-His(1-Me)-OH is a valuable compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an excellent choice for researchers in the fields of biochemistry and medicinal chemistry. Its unique structure, characterized by the presence of a 1-methylimidazole side chain, allows for specific interactions in biological systems, facilitating the design of novel therapeutics and biologically active peptides.

In practical applications, Boc-D-His(1-Me)-OH is particularly beneficial in the synthesis of histidine-containing peptides, which are essential for various biological functions, including enzyme catalysis and metal ion binding. The compound's ability to improve the yield and purity of peptide products makes it a preferred choice among professionals in pharmaceutical and biotechnology industries. Its versatility and effectiveness in enhancing peptide stability and functionality underscore its significance in advancing research and development efforts.

Synonyms
Boc-D-His(Nim-Me)-OH
CAS Number
200871-52-9
Purity
≥ 99% (TLC)
Molecular Formula
C12H19N3O4
Molecular Weight
269.3
MDL Number
MFCD00237544
PubChem ID
21935430
Melting Point
111-115 ºC
Appearance
White solid
Conditions
Store at ≤-4°C
General Information
Synonyms
Boc-D-His(Nim-Me)-OH
CAS Number
200871-52-9
Purity
≥ 99% (TLC)
Molecular Formula
C12H19N3O4
Molecular Weight
269.3
MDL Number
MFCD00237544
PubChem ID
21935430
Melting Point
111-115 ºC
Appearance
White solid
Conditions
Store at ≤-4°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-His(1-Me)-OH is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those that require histidine residues. Its protective Boc group allows for selective reactions, making it easier to construct complex peptide chains.
  • Drug Development: In pharmaceutical research, Boc-D-His(1-Me)-OH is used to create drug candidates that target specific biological pathways. Its unique structure can enhance the efficacy of therapeutic agents, particularly in oncology and immunology.
  • Bioconjugation: This chemical is employed in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules. This is particularly useful in developing targeted drug delivery systems and diagnostic tools.
  • Protein Engineering: Researchers use Boc-D-His(1-Me)-OH to modify proteins, improving their stability and functionality. This application is crucial in creating enzymes with enhanced activity or specificity for industrial processes.
  • Research in Molecular Biology: The compound is valuable in studying protein interactions and functions due to its ability to mimic natural amino acids. This helps scientists understand complex biological systems and develop new therapeutic strategies.

Citations