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Catalog Number:
11182
CAS Number:
136083-57-3
Fmoc-D-aspartic acid
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-D-Asp-OH
Documents
$18.53 /1G
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Product Information

Fmoc-D-aspartic acid is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis of peptides, making it an essential building block for researchers in the fields of biochemistry and medicinal chemistry. Its unique structure not only enhances the stability of peptides but also facilitates the incorporation of D-aspartic acid into various sequences, which is crucial for studying protein interactions and enzymatic functions.

In addition to its role in peptide synthesis, Fmoc-D-aspartic acid has potential applications in the development of pharmaceuticals targeting neurological disorders, given the importance of aspartic acid in neurotransmission. Researchers appreciate its ease of use and compatibility with standard coupling reagents, which streamlines the synthesis process. Furthermore, its ability to form stable peptide bonds makes it a preferred choice for creating complex peptide libraries for drug discovery. Overall, Fmoc-D-aspartic acid stands out for its practicality and effectiveness in advancing research in peptide chemistry and related fields.

Synonyms
Fmoc-D-Asp-OH
CAS Number
136083-57-3
Purity
≥ 97% (HPLC)
Molecular Formula
C19H17NO6
Molecular Weight
355.35
MDL Number
MFCD01318740
PubChem ID
3671531
Melting Point
182-187 °C
Appearance
White powder
Optical Rotation
[α]D20 = +25 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Asp-OH
CAS Number
136083-57-3
Purity
≥ 97% (HPLC)
Molecular Formula
C19H17NO6
Molecular Weight
355.35
MDL Number
MFCD01318740
PubChem ID
3671531
Melting Point
182-187 °C
Appearance
White powder
Optical Rotation
[α]D20 = +25 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-aspartic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound is commonly used as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Researchers leverage its properties to develop new pharmaceuticals, particularly in the design of neuropeptides and other biologically active compounds.
  • Bioconjugation: It serves as a key building block in bioconjugation strategies, facilitating the attachment of peptides to various biomolecules for targeted drug delivery systems.
  • Research in Neuroscience: The compound is utilized in studies related to neurotransmitter pathways, helping scientists understand the role of aspartic acid in synaptic transmission and neuropharmacology.
  • Custom Synthesis: Its versatility makes it a popular choice for custom synthesis in academic and industrial laboratories, where tailored compounds are needed for specific research applications.

Citations