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Catalog Number:
11181
CAS Number:
150009-58-8
Fmoc-D-aspartic acid β-benzyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Asp(OBzl)-OH
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Product Information

Fmoc-D-aspartic acid b-benzyl ester is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of the amino group during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it an invaluable tool for researchers in the fields of medicinal chemistry and biochemistry. The b-benzyl ester moiety enhances the compound's lipophilicity, facilitating better permeation through biological membranes, which is particularly beneficial in drug formulation and delivery applications.

This compound is especially relevant for those working on the synthesis of complex peptides and proteins, as it provides a stable and easily removable protecting group. Its applications extend to the development of therapeutic peptides, where precise control over amino acid sequences is crucial. Researchers can leverage Fmoc-D-aspartic acid b-benzyl ester to create novel compounds with enhanced biological activity, thereby advancing drug discovery and development efforts.

Synonyms
Fmoc-D-Asp(OBzl)-OH
CAS Number
150009-58-8
Purity
≥ 99% (HPLC)
Molecular Formula
C26H23NO6
Molecular Weight
445.5
MDL Number
MFCD00273445
PubChem ID
4089644
Melting Point
120-128 °C
Optical Rotation
[α]D20 = +21 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Asp(OBzl)-OH
CAS Number
150009-58-8
Purity
≥ 99% (HPLC)
Molecular Formula
C26H23NO6
Molecular Weight
445.5
MDL Number
MFCD00273445
PubChem ID
4089644
Melting Point
120-128 °C
Optical Rotation
[α]D20 = +21 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-aspartic acid b-benzyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It is used in the design of pharmaceutical compounds, particularly in the development of neuroactive peptides that can target specific receptors in the nervous system.
  • Bioconjugation: This chemical facilitates the attachment of biomolecules to surfaces or other molecules, enhancing the efficacy of drug delivery systems and diagnostic tools.
  • Research in Neuroscience: It plays a crucial role in studying neurotransmitter pathways, helping researchers understand the mechanisms of neurodegenerative diseases and potential therapeutic interventions.
  • Custom Synthesis: The compound is valuable for researchers needing tailored solutions for specific applications, providing flexibility in designing novel compounds with desired properties.

Citations