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Catalog Number:
11180
CAS Number:
130752-32-8
Nα-Fmoc-D-arginine hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Arg-OH·HCl
Documents
$120.88 /250MG
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Product Information

Na-Fmoc-D-arginine hydrochloride is a highly valued compound in the field of peptide synthesis and biochemistry. This derivative of arginine features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it a preferred choice for researchers focused on developing complex peptide sequences. The compound's stability and solubility in organic solvents enhance its usability in various laboratory settings, facilitating streamlined workflows in peptide synthesis.

In practical applications, Na-Fmoc-D-arginine hydrochloride is widely utilized in the production of bioactive peptides, which have significant implications in drug development and therapeutic research. Its ability to provide controlled release of the amino group allows for precise modifications, enabling the creation of peptides with tailored biological activities. This compound is particularly beneficial in the pharmaceutical industry, where it supports the design of novel therapeutics targeting a range of diseases. Researchers appreciate its reliability and efficiency, making it an indispensable tool in peptide chemistry.

Synonyms
Fmoc-D-Arg-OH·HCl
CAS Number
130752-32-8
Purity
≥ 98% (HPLC)
Molecular Formula
C21H24N4O4·HCl
Molecular Weight
432.91
MDL Number
MFCD01318732
PubChem ID
4439755
Melting Point
148 - 151 °C
Appearance
White powder
Optical Rotation
[a]20D = -15 ± 2 ° (C=0.5 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Arg-OH·HCl
CAS Number
130752-32-8
Purity
≥ 98% (HPLC)
Molecular Formula
C21H24N4O4·HCl
Molecular Weight
432.91
MDL Number
MFCD01318732
PubChem ID
4439755
Melting Point
148 - 151 °C
Appearance
White powder
Optical Rotation
[a]20D = -15 ± 2 ° (C=0.5 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-D-arginine hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of D-arginine into peptide chains, which can enhance biological activity.
  • Drug Development: Its role in modifying peptide structures makes it valuable in the pharmaceutical industry for developing new therapeutics, especially in targeting specific receptors or pathways in diseases.
  • Bioconjugation: Researchers use this chemical to create bioconjugates, linking peptides to other molecules like drugs or imaging agents, which can improve the efficacy and specificity of treatments.
  • Protein Engineering: In the field of protein engineering, it is employed to introduce specific functionalities into proteins, aiding in the design of novel proteins with desired properties for research or therapeutic use.
  • Diagnostics: The compound can be utilized in the development of diagnostic tools, particularly in assays that require high specificity and sensitivity, contributing to better disease detection methods.

Citations