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Catalog Number:
11179
CAS Number:
163558-30-3
Fmoc-S-sulfo-L-cysteine disodium
Purity:
≥ 99.8% (HPLC, Chiral purity)
Synonym(s):
Fmoc-L-Cys(SO3H)-OH·disodium salt
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Product Information

Fmoc-S-sulfo-L-cysteine disodium is a versatile and valuable compound widely utilized in peptide synthesis and bioconjugation applications. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during solid-phase peptide synthesis. Its sulfonate group enhances solubility in aqueous solutions, making it particularly advantageous for researchers working in biological environments. Fmoc-S-sulfo-L-cysteine disodium is especially useful in the development of peptide-based therapeutics and diagnostics, where the introduction of sulfhydryl groups is critical for forming disulfide bonds and facilitating protein folding.

This compound's unique properties enable its application in various fields, including drug development, biomaterials, and nanotechnology. Researchers can leverage its reactivity to create conjugates with proteins, antibodies, or other biomolecules, enhancing the efficacy and specificity of their formulations. The ability to easily manipulate the Fmoc group allows for streamlined synthesis processes, making it an ideal choice for both academic and industrial laboratories focused on peptide research and development.

Synonyms
Fmoc-L-Cys(SO3H)-OH·disodium salt
CAS Number
163558-30-3
Purity
≥ 99.8% (HPLC, Chiral purity)
Molecular Formula
C18H15NNa2O7S2
Molecular Weight
467.43
MDL Number
MFCD00237016
PubChem ID
91977576
Appearance
White powder
Optical Rotation
[a]D24 = -41.5 ± 1.5º (C=1 in Water)
Conditions
Store at RT
General Information
Synonyms
Fmoc-L-Cys(SO3H)-OH·disodium salt
CAS Number
163558-30-3
Purity
≥ 99.8% (HPLC, Chiral purity)
Molecular Formula
C18H15NNa2O7S2
Molecular Weight
467.43
MDL Number
MFCD00237016
PubChem ID
91977576
Appearance
White powder
Optical Rotation
[a]D24 = -41.5 ± 1.5º (C=1 in Water)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-S-sulfo-L-cysteine disodium is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enabling the creation of complex and functional peptides for various applications.
  • Drug Development: It plays a crucial role in developing novel therapeutics, especially in targeting specific proteins, which is essential in the pharmaceutical industry for creating effective drugs.
  • Bioconjugation: Researchers use it for bioconjugation processes, allowing the attachment of biomolecules to surfaces or other molecules, enhancing the efficacy of diagnostics and therapeutics.
  • Protein Engineering: The compound is valuable in protein engineering, facilitating the introduction of specific functionalities in proteins, which can improve their stability and activity in various applications.
  • Analytical Chemistry: It is utilized in analytical methods, such as mass spectrometry, to improve the detection and characterization of biomolecules, providing researchers with detailed insights into molecular structures.

Citations