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Catalog Number:
10099
CAS Number:
402-71-1
Tosyl-L-Phenylalanine chloromethylketone
Purity:
≥ 98% (TLC)
Synonym(s):
Tos-L-Phe-CMK, TPCK
Hazmat
Documents
$95.00 /250MG
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Product Information

Tosyl-L-Phenylalanine chloromethylketone is a versatile compound widely utilized in the field of organic synthesis and medicinal chemistry. This compound serves as a valuable intermediate in the production of various pharmaceuticals and biologically active molecules. Its unique structure allows for selective modifications, making it an essential building block in the synthesis of peptide-based drugs and inhibitors. Researchers appreciate its ability to facilitate the introduction of functional groups, enhancing the efficacy and specificity of drug candidates.

In addition to its applications in drug development, Tosyl-L-Phenylalanine chloromethylketone is also employed in the synthesis of complex natural products and in the study of enzyme mechanisms. Its stability and reactivity under mild conditions make it an attractive choice for chemists looking to optimize reaction conditions and improve yields. With its broad range of applications, this compound is an indispensable tool for researchers and industry professionals aiming to innovate in the pharmaceutical and chemical sectors.

Synonyms
Tos-L-Phe-CMK, TPCK
CAS Number
402-71-1
Purity
≥ 98% (TLC)
Molecular Formula
C17H18ClNO3S
Molecular Weight
351.85
MDL Number
MFCD00000935
PubChem ID
9824
Melting Point
106 - 110 °C
Appearance
White powder
Optical Rotation
[a]D24 = -86.0 ± 2º (C=1 in EtOH abs.)
Conditions
Store at 0 - 8 °C
Warnings
Corrosive! Irritant!
General Information
Synonyms
Tos-L-Phe-CMK, TPCK
CAS Number
402-71-1
Purity
≥ 98% (TLC)
Molecular Formula
C17H18ClNO3S
Molecular Weight
351.85
MDL Number
MFCD00000935
PubChem ID
9824
Melting Point
106 - 110 °C
Appearance
White powder
Optical Rotation
[a]D24 = -86.0 ± 2º (C=1 in EtOH abs.)
Conditions
Store at 0 - 8 °C
Warnings
Corrosive! Irritant!
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
Corrosive! Irritant!
Applications

Tosyl-L-Phenylalanine chloromethylketone is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable reagent in the synthesis of peptides, allowing researchers to create complex structures with high specificity and efficiency.
  • Enzyme Inhibition Studies: It is often used to study enzyme mechanisms by acting as a selective inhibitor, providing insights into enzyme activity and potential therapeutic targets.
  • Drug Development: The compound plays a crucial role in the pharmaceutical industry for developing new drugs, particularly in designing inhibitors for various biological pathways.
  • Bioconjugation: It is employed in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing drug delivery systems and diagnostic tools.
  • Research on Protein Interactions: Researchers use this chemical to investigate protein-protein interactions, which is essential for understanding cellular processes and developing new therapeutic strategies.

Citations