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Catalog Number:
10097
CAS Number:
4272-74-6
Nα-Tosyl-L-lysine chloromethylketone hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
Tos-L-Lys-CMK·HCl
Documents
$174.00 /100MG
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Product Information

Na-Tosyl-L-lysine chloromethylketone hydrochloride is a versatile reagent widely utilized in peptide synthesis and bioconjugation applications. This compound serves as a valuable tool for researchers in the fields of medicinal chemistry and biochemistry, particularly in the development of peptide-based therapeutics. Its unique structure allows for selective modification of amino acids, facilitating the introduction of various functional groups into peptides. This capability enhances the diversity of peptide libraries, which is crucial for drug discovery and development.

Additionally, Na-Tosyl-L-lysine chloromethylketone hydrochloride is recognized for its role in the synthesis of peptide derivatives with improved biological activity. Its ability to act as a protecting group for amino acids during synthesis makes it an essential component in the preparation of complex peptides. Researchers appreciate its stability and ease of use, which streamline the synthesis process and improve yields. With its broad applicability in pharmaceutical research and development, this compound is an indispensable asset for professionals aiming to innovate in peptide chemistry.

Synonyms
Tos-L-Lys-CMK·HCl
CAS Number
4272-74-6
Purity
≥ 98% (HPLC)
Molecular Formula
C14H21ClN2O3S·HCl
Molecular Weight
369.31
MDL Number
MFCD00065395
PubChem ID
23335676
Melting Point
155 - 160 °C (Lit.)
Appearance
White to off-white to yellowish powder
Optical Rotation
[a]D24 = -9 ± 2 °
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Tos-L-Lys-CMK·HCl
CAS Number
4272-74-6
Purity
≥ 98% (HPLC)
Molecular Formula
C14H21ClN2O3S·HCl
Molecular Weight
369.31
MDL Number
MFCD00065395
PubChem ID
23335676
Melting Point
155 - 160 °C (Lit.)
Appearance
White to off-white to yellowish powder
Optical Rotation
[a]D24 = -9 ± 2 °
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Tosyl-L-lysine chloromethylketone hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a powerful reagent in the synthesis of peptides, allowing researchers to create complex structures with high specificity and yield.
  • Protein Modification: It is commonly used to modify proteins, enabling scientists to study protein interactions and functions, which is crucial in drug development and biotechnology.
  • Enzyme Inhibition Studies: The compound acts as an effective inhibitor for certain enzymes, making it valuable in pharmacological research to explore enzyme activity and potential therapeutic targets.
  • Bioconjugation: It facilitates bioconjugation processes, where biomolecules are linked to other entities, enhancing the development of targeted drug delivery systems.
  • Research in Neuroscience: This chemical is applied in studies related to neurotransmitter systems, helping researchers understand neurological pathways and develop treatments for neurological disorders.

Citations