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Catalog Number:
10092
CAS Number:
110771-95-4
Tosyl-D-proline
Purity:
≥ 98% (TLC)
Synonym(s):
Tos-D-Pro-OH
Documents
$115.90 /1G
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Product Information

Tosyl-D-proline is a versatile compound widely recognized for its applications in organic synthesis and medicinal chemistry. This sulfonamide derivative of proline features a tosyl group, enhancing its reactivity and making it an invaluable building block in the development of pharmaceuticals and agrochemicals. Its unique structure allows for the efficient formation of peptide bonds, which is crucial in peptide synthesis, particularly in the creation of biologically active compounds. Researchers appreciate Tosyl-D-proline for its ability to facilitate stereoselective reactions, making it a preferred choice in asymmetric synthesis.

In addition to its synthetic utility, Tosyl-D-proline has shown potential in the development of enzyme inhibitors and other therapeutic agents, contributing to advancements in drug discovery. Its favorable properties, such as stability and solubility, further enhance its applicability in various chemical processes. Whether you are involved in academic research or industrial applications, Tosyl-D-proline stands out as a reliable and effective reagent that can streamline your synthesis efforts and improve the efficiency of your projects.

Synonyms
Tos-D-Pro-OH
CAS Number
110771-95-4
Purity
≥ 98% (TLC)
Molecular Formula
C12H15NO4S
Molecular Weight
269.32
MDL Number
MFCD00237289
PubChem ID
563461
Melting Point
55-60 ºC
Appearance
White powder
Optical Rotation
[a]D24 = +152 ± 2º (C=2.3% in H2O and 2 aquimolar NaOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Tos-D-Pro-OH
CAS Number
110771-95-4
Purity
≥ 98% (TLC)
Molecular Formula
C12H15NO4S
Molecular Weight
269.32
MDL Number
MFCD00237289
PubChem ID
563461
Melting Point
55-60 ºC
Appearance
White powder
Optical Rotation
[a]D24 = +152 ± 2º (C=2.3% in H2O and 2 aquimolar NaOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Tosyl-D-proline is widely utilized in research focused on:

  • Asymmetric Synthesis: This compound serves as a chiral auxiliary in the synthesis of enantiomerically pure compounds, making it invaluable in the pharmaceutical industry for developing new drugs.
  • Peptide Synthesis: It is used in the formation of peptides, aiding researchers in creating specific sequences that can lead to novel therapeutic agents.
  • Biocatalysis: Tosyl-D-proline acts as a catalyst in various biocatalytic reactions, enhancing reaction rates and selectivity, which is crucial in green chemistry applications.
  • Drug Development: Its unique properties allow for the modification of drug candidates, improving their efficacy and reducing side effects, thus streamlining the drug discovery process.
  • Research in Neuroscience: The compound is explored for its potential effects on neurological pathways, providing insights into treatments for neurological disorders.

Citations