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Catalog Number:
08086
CAS Number:
116783-35-8
Fmoc-O-β-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranosyl)-L-threonine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-Thr(GalNAc(Ac)3-α-D)-OH
Documents
$338.01 /25MG
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Product Information

Fmoc-O-b-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-a-D-galactopyranosyl)-L-threonine is a specialized amino acid derivative that plays a crucial role in peptide synthesis and carbohydrate chemistry. This compound is particularly valued in the field of medicinal chemistry and biochemistry for its ability to facilitate the development of glycopeptides, which are essential in the creation of therapeutics and vaccines. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group, allows for selective deprotection during synthesis, making it an ideal choice for researchers focused on complex peptide assembly.

The compound's tri-O-acetylated galactopyranosyl moiety enhances its solubility and stability, which is beneficial for various applications, including drug formulation and delivery systems. Researchers have utilized this compound in the synthesis of glycoproteins and in studies aimed at understanding carbohydrate-protein interactions. Its versatility and effectiveness in promoting efficient coupling reactions make it a valuable asset in both academic and industrial laboratories, particularly for those engaged in the development of novel therapeutic agents.

Synonyms
Fmoc-L-Thr(GalNAc(Ac)3-α-D)-OH
CAS Number
116783-35-8
Purity
≥ 97% (HPLC)
Molecular Formula
C33H38N2O13
Molecular Weight
670.67
MDL Number
MFCD00171374
PubChem ID
14410191
Appearance
White to off-white solid
Conditions
Store at ≤ -20 °C
General Information
Synonyms
Fmoc-L-Thr(GalNAc(Ac)3-α-D)-OH
CAS Number
116783-35-8
Purity
≥ 97% (HPLC)
Molecular Formula
C33H38N2O13
Molecular Weight
670.67
MDL Number
MFCD00171374
PubChem ID
14410191
Appearance
White to off-white solid
Conditions
Store at ≤ -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-b-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-a-D-galactopyranosyl)-L-threonine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences with high purity.
  • Glycopeptide Development: It is instrumental in developing glycopeptides, which are important for studying protein interactions and functions, particularly in the fields of immunology and cancer research.
  • Drug Design: The compound can be used in the design of novel therapeutics, especially those targeting specific glycan structures, enhancing the specificity and efficacy of drug candidates.
  • Bioconjugation: This chemical is valuable for bioconjugation processes, where it can be attached to various biomolecules, improving their stability and bioavailability in pharmaceutical applications.
  • Research in Carbohydrate Chemistry: It plays a significant role in carbohydrate chemistry research, aiding in the understanding of carbohydrate-protein interactions and their implications in biological systems.

Citations