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Catalog Number:
07968
CAS Number:
133407-82-6
Calpain Inhibitor IV
Purity:
≥ 99% (HPLC)
Synonym(s):
Z-Leu-Leu-Leu-aldehyde
Documents
$312.27 /5MG
Pack Size Availability Price
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Product Information

Calpain Inhibitor IV is a potent and selective inhibitor of calpain, a calcium-dependent cysteine protease involved in various cellular processes, including apoptosis and cell signaling. This compound is particularly valuable in research settings focused on neurodegenerative diseases, cancer, and muscle disorders, where calpain activity plays a crucial role in disease progression. By inhibiting calpain, researchers can explore therapeutic strategies that may mitigate cellular damage and promote cell survival.

In addition to its applications in basic research, Calpain Inhibitor IV has shown promise in drug development, particularly in the formulation of treatments aimed at neuroprotection and muscle preservation. Its unique structure allows for high specificity, reducing off-target effects compared to other inhibitors. This specificity makes it an essential tool for scientists investigating the molecular mechanisms of diseases and developing targeted therapies. With its ability to modulate calpain activity, Calpain Inhibitor IV stands out as a critical compound for advancing both academic research and clinical applications.

Synonyms
Z-Leu-Leu-Leu-aldehyde
CAS Number
133407-82-6
Purity
≥ 99% (HPLC)
Molecular Formula
C26H41N3O5
Molecular Weight
475.63
MDL Number
MFCD00674886
PubChem ID
6914692
Appearance
White powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Z-Leu-Leu-Leu-aldehyde
CAS Number
133407-82-6
Purity
≥ 99% (HPLC)
Molecular Formula
C26H41N3O5
Molecular Weight
475.63
MDL Number
MFCD00674886
PubChem ID
6914692
Appearance
White powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Calpain Inhibitor IV is widely utilized in research focused on:

  • Neuroscience Research: This compound is instrumental in studying neurodegenerative diseases, as it helps in understanding the role of calpain in neuronal cell death and survival mechanisms.
  • Drug Development: It serves as a valuable tool in the development of new therapeutic agents targeting calpain-related disorders, offering insights into potential treatments for conditions like Alzheimer's and Parkinson's disease.
  • Cell Biology: Researchers use it to investigate cellular processes such as apoptosis and cell migration, providing a clearer picture of how calpain activity influences these critical functions.
  • Cardiovascular Studies: The compound is applied in studies related to heart diseases, where calpain's role in cardiac remodeling and hypertrophy is explored, aiding in the search for effective heart disease therapies.
  • Cancer Research: It is utilized to examine the involvement of calpain in cancer cell invasion and metastasis, helping to identify potential targets for cancer treatment strategies.

Citations