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Catalog Number:
07398
CAS Number:
205526-30-3
Fmoc-3,4,5-trifluoro-L-phenylalanine
Purity:
≥ 98% (Assay)
Synonym(s):
Fmoc-L-Phe(3,4,5-trifluoro)-OH
Documents
$65.00 /100MG
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Product Information

Fmoc-3,4,5-trifluoro-L-phenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique trifluoromethyl group, which enhances its biochemical properties, making it an excellent choice for researchers focused on creating fluorinated peptides with improved stability and bioactivity. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing a straightforward deprotection process, facilitating efficient synthesis workflows.

In the pharmaceutical industry, Fmoc-3,4,5-trifluoro-L-phenylalanine is particularly advantageous for developing novel therapeutics, especially in the field of oncology and neuropharmacology, where fluorinated compounds often exhibit enhanced potency and selectivity. Its unique properties make it an essential building block for researchers aiming to explore new therapeutic avenues or improve existing peptide-based drugs. With its combination of stability, ease of use, and potential for enhanced biological activity, this compound stands out as a key player in modern peptide chemistry.

Synonyms
Fmoc-L-Phe(3,4,5-trifluoro)-OH
CAS Number
205526-30-3
Purity
≥ 98% (Assay)
Molecular Formula
C24H18F3NO4
Molecular Weight
441.41
MDL Number
MFCD00797583
PubChem ID
53395418
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(3,4,5-trifluoro)-OH
CAS Number
205526-30-3
Purity
≥ 98% (Assay)
Molecular Formula
C24H18F3NO4
Molecular Weight
441.41
MDL Number
MFCD00797583
PubChem ID
53395418
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3,4,5-trifluoro-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This chemical serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity and yield.
  • Fluorinated Amino Acids: Its unique trifluoromethyl group enhances the properties of peptides, making them more stable and resistant to enzymatic degradation, which is beneficial in drug development and therapeutic applications.
  • Bioconjugation: The Fmoc protecting group allows for selective reactions in bioconjugation processes, facilitating the attachment of peptides to various biomolecules, which is crucial in the development of targeted drug delivery systems.
  • Research in Structural Biology: This compound is used in the study of protein structures and functions, providing insights into the role of fluorinated amino acids in protein stability and interactions.
  • Pharmaceutical Development: Its application in medicinal chemistry helps in designing novel therapeutics with improved pharmacokinetic properties, making it valuable in the pharmaceutical industry.

Citations