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Catalog Number:
07336
CAS Number:
218457-81-9
Fmoc-3,4-dimethoxy-D-phenylalanine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-D-Phe(3,4-dimethoxy)-OH, Fmoc-3,4-dimethoxy-D-Phe-OH, (R-Fmoc-2-amino-3-(3,4-dimethoxyphenyl)propionic acid
Documents
$86.23 /100MG
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Product Information

Fmoc-3,4-dimethoxy-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound, recognized for its protective Fmoc (fluorenylmethyloxycarbonyl) group, facilitates the efficient assembly of peptides by providing a stable and easily removable protecting group. Its unique structure, featuring a dimethoxy substitution on the aromatic ring, enhances its solubility and reactivity, making it an ideal choice for researchers engaged in the synthesis of complex peptides and biologically active compounds.

In the pharmaceutical industry, Fmoc-3,4-dimethoxy-D-phenylalanine plays a critical role in the development of peptide-based therapeutics, including those targeting specific receptors or exhibiting unique biological activities. Its application extends to the creation of peptide libraries for drug discovery, allowing researchers to explore a wide range of potential drug candidates. By incorporating this compound into their workflows, scientists can streamline the synthesis process, improve yields, and enhance the overall efficiency of their research projects.

Synonyms
Fmoc-D-Phe(3,4-dimethoxy)-OH, Fmoc-3,4-dimethoxy-D-Phe-OH, (R-Fmoc-2-amino-3-(3,4-dimethoxyphenyl)propionic acid
CAS Number
218457-81-9
Purity
≥ 97% (HPLC)
Molecular Formula
C26H25NO6
Molecular Weight
447.5
MDL Number
MFCD01317731
PubChem ID
4712577
Appearance
White powder
Optical Rotation
[a]20D = 24 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Phe(3,4-dimethoxy)-OH, Fmoc-3,4-dimethoxy-D-Phe-OH, (R-Fmoc-2-amino-3-(3,4-dimethoxyphenyl)propionic acid
CAS Number
218457-81-9
Purity
≥ 97% (HPLC)
Molecular Formula
C26H25NO6
Molecular Weight
447.5
MDL Number
MFCD01317731
PubChem ID
4712577
Appearance
White powder
Optical Rotation
[a]20D = 24 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3,4-dimethoxy-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as an essential building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing new drugs, especially in designing peptide-based therapeutics that target specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach drugs or imaging agents to biomolecules, enhancing the efficacy and targeting of therapeutic agents.
  • Research in Neuroscience: Researchers utilize this compound to study neuropeptides and their interactions in the nervous system, contributing to advancements in understanding neurological disorders.
  • Custom Peptide Libraries: It is instrumental in creating custom peptide libraries for screening and discovery in various biological assays, facilitating the identification of potential drug candidates.

Citations