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Catalog Number:
07324
CAS Number:
221352-74-5
(2S,4S)-Boc-4-amino-1-Fmoc-pyrrolidine-2-carboxylic acid
Purity:
≥ 95% (HPLC)
Documents
$72.31 /100MG
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Product Information

The compound (2S,4S)-Boc-4-amino-1-Fmoc-pyrrolidine-2-carboxylic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique combination of a Boc (tert-butyloxycarbonyl) protecting group and an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group, which allows for selective deprotection during the synthesis of complex peptides. Its chiral centers enhance its relevance in the development of enantiomerically pure compounds, making it an essential tool for researchers focused on drug discovery and development.

In addition to its applications in peptide synthesis, this compound is also valuable in the production of biologically active molecules, including pharmaceuticals and agrochemicals. Its stability and compatibility with various coupling reagents make it an ideal choice for chemists looking to streamline their synthetic processes. The ability to selectively manipulate its functional groups allows for the creation of diverse molecular architectures, further expanding its utility in both academic and industrial settings.

CAS Number
221352-74-5
Purity
≥ 95% (HPLC)
Molecular Formula
C25H28N2O6
Molecular Weight
452.6
MDL Number
MFCD02179641
PubChem ID
4712571
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -35 ± 2º (C=1 in CHCl3) [a]D20 = - 29 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
CAS Number
221352-74-5
Purity
≥ 95% (HPLC)
Molecular Formula
C25H28N2O6
Molecular Weight
452.6
MDL Number
MFCD02179641
PubChem ID
4712571
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -35 ± 2º (C=1 in CHCl3) [a]D20 = - 29 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2S,4S)-Boc-4-amino-1-Fmoc-pyrrolidine-2-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the pharmaceutical industry, where it helps create therapeutic proteins and peptides with enhanced stability and bioactivity.
  • Drug Development: It plays a crucial role in the development of new drugs, especially in the design of inhibitors and modulators for various biological pathways, aiding researchers in creating targeted therapies.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing scientists to attach drugs or imaging agents to biomolecules, which is essential in developing targeted drug delivery systems.
  • Research in Neuroscience: Its unique structure makes it valuable in neuroscience research, particularly in studying neuropeptides and their roles in brain function, which can lead to advancements in treating neurological disorders.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis services for this compound, providing researchers with tailored solutions that meet specific project requirements, thus saving time and resources in their studies.

Citations