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Catalog Number:
07264
CAS Number:
220497-61-0
Fmoc-L-cyclopentylglycine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-Gly(cyclopentyl)-OH, (S-2-Cyclopentyl-2-(Fmoc-amino)-acetic acid
Documents
$79.22 /250MG
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Product Information

Fmoc-L-cyclopentylglycine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a cyclopentyl side chain, which imparts unique steric and electronic properties, making it an excellent choice for enhancing the stability and bioactivity of peptides. Its fluorenylmethoxycarbonyl (Fmoc) protecting group allows for easy incorporation into peptide chains while providing robust protection during synthesis. Researchers appreciate its role in developing peptide-based therapeutics, particularly in areas such as cancer treatment and neuropharmacology, where specific amino acid configurations can significantly influence biological activity.

The unique structure of Fmoc-L-cyclopentylglycine not only facilitates the synthesis of complex peptides but also enhances their pharmacological profiles. Its application in solid-phase peptide synthesis (SPPS) allows for efficient assembly of peptides with improved solubility and stability. This compound is particularly beneficial for researchers looking to create novel peptide sequences that require specific conformational characteristics. With its favorable properties, Fmoc-L-cyclopentylglycine stands out as a crucial building block for innovative research and development in the pharmaceutical industry.

Synonyms
Fmoc-Gly(cyclopentyl)-OH, (S-2-Cyclopentyl-2-(Fmoc-amino)-acetic acid
CAS Number
220497-61-0
Purity
≥ 98% (HPLC)
Molecular Formula
C22H23NO4
Molecular Weight
365.2
MDL Number
MFCD01311751
PubChem ID
66615358
Appearance
White powder
Optical Rotation
[a]D20 = -18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-Gly(cyclopentyl)-OH, (S-2-Cyclopentyl-2-(Fmoc-amino)-acetic acid
CAS Number
220497-61-0
Purity
≥ 98% (HPLC)
Molecular Formula
C22H23NO4
Molecular Weight
365.2
MDL Number
MFCD01311751
PubChem ID
66615358
Appearance
White powder
Optical Rotation
[a]D20 = -18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-cyclopentylglycine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity.
  • Drug Development: It plays a crucial role in the design of peptide-based drugs, offering unique properties that can enhance the efficacy and specificity of therapeutic agents in treating various diseases.
  • Bioconjugation: Fmoc-L-cyclopentylglycine can be used in bioconjugation processes, facilitating the attachment of peptides to other biomolecules, which is essential in developing targeted drug delivery systems.
  • Research in Neuroscience: This compound is utilized in studies related to neuropeptides, helping researchers understand the role of specific peptides in neurological functions and potential treatments for neurological disorders.
  • Custom Peptide Libraries: It is instrumental in creating custom peptide libraries for high-throughput screening, enabling researchers to discover new bioactive peptides for various applications in biotechnology and pharmaceuticals.

Citations