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Catalog Number:
07111
CAS Number:
1272755-49-3
Fmoc-O-2-chlorotrityl-D-tyrosine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Tyr(2-ClTrt)-OH
Documents
$74.81 /1G
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Product Information

Fmoc-O-2-chlorotrityl-D-tyrosine is a highly versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is widely recognized for its stability and ease of removal under mild conditions, making it an ideal choice for solid-phase peptide synthesis. The incorporation of the 2-chlorotrityl group enhances its utility in various coupling reactions, allowing for efficient and selective modifications in complex peptide sequences.

Researchers and industry professionals can leverage Fmoc-O-2-chlorotrityl-D-tyrosine in the development of therapeutic peptides, particularly in the fields of oncology and neurology, where precise amino acid sequences are critical for biological activity. Its ability to facilitate the synthesis of modified peptides opens avenues for creating novel compounds with improved efficacy and specificity. With its robust properties and practical applications, this compound stands out as a valuable tool for advancing peptide chemistry and drug discovery.

Synonyms
Fmoc-D-Tyr(2-ClTrt)-OH
CAS Number
1272755-49-3
Purity
≥ 99% (HPLC)
Molecular Formula
C43H34NO5Cl
Molecular Weight
680.2
MDL Number
MFCD01632437
PubChem ID
75627311
Melting Point
158-163 ºC
Appearance
Off-white powder
Optical Rotation
[a]D20 = +28 ± 2º (C=2, EtOAc)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Tyr(2-ClTrt)-OH
CAS Number
1272755-49-3
Purity
≥ 99% (HPLC)
Molecular Formula
C43H34NO5Cl
Molecular Weight
680.2
MDL Number
MFCD01632437
PubChem ID
75627311
Melting Point
158-163 ºC
Appearance
Off-white powder
Optical Rotation
[a]D20 = +28 ± 2º (C=2, EtOAc)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-2-chlorotrityl-D-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, enabling the creation of complex peptides with high purity and yield.
  • Drug Development: Its application in medicinal chemistry allows researchers to modify peptide structures, enhancing their efficacy and stability for potential therapeutic use.
  • Bioconjugation: The unique functional groups facilitate the attachment of peptides to various biomolecules, aiding in the development of targeted drug delivery systems.
  • Research in Neuroscience: By incorporating this compound into peptide sequences, scientists can study neuropeptide interactions, contributing to a better understanding of neurological disorders.
  • Analytical Chemistry: It is used in the development of analytical methods for peptide characterization, providing insights into their structure and function.

Citations